Phakathi kwenani elikhulu lamagosa e-pharmacological ekuxazulula iingxaki ngamathambo emathumbu, i-Ftalazol yenye yezona zixhaphakileyo kwaye ngexesha elifanayo nezidakamizwa ezingabizi. Esi sidakamizwa sisebenza njenge-arhente esebenzayo. Ungowesigaba sulfonamide. Isilwanyana sinomphumo onobungozi kwiibhaktheriya ezibangela ukusuleleka kwisistim sokutya. Ukongeza, iFtalazol inefuthe elichasayo, kwaye iphinde ikhuthaze imveliso ye-glucocorticosteroids - amahomoni ayimvelo avimbela iinkqubo zokuvuvukala emzimbeni.
Inkcazo yezilwanyana zeFtalazol
Into esebenzayo ye-phthalazole yi-phthalylsulfatizole, uncedisi yi talc, i-calcium stearate kunye nesitashi samatat. I-Phthalazol ikhiqizwa kuphela kwiipilisi zokungeniswa kwe-10, ngokungaqhelekanga iziqhekeza ezingama-20 kwisitya. Iibhilethi ziyingcipheko emhlophe kunye nomngcipheko kunye nesimo.
Emva kokuba uthathe amayeza ayengaxhamli ngegazi, kwaye "ukusebenza" kuqala kuphela emva kokushaya intlungu. Ininzi yento esebenzayo igcinwa kwisigxina sokugaya, iqokelela kwaye inefuthe elifanelekileyo le-antibiotic.
Ziziphi iipilisi zeFtalazol ezisetyenziselwa?
I-Phthalazole inefuthe lokunyanga kwezi zifo zilandelayo:
- ukutyhelwa kokutya (ukudakwa komzimba);
- isifo somhlaza;
- enterocolitis;
- isilonda, isilly-necrotic colitis;
- i-gastroenteritis yomsuka osulelayo;
- isifo sohudo;
- izifo zakwaSalmonella;
- dysbiosis;
- shigellosis;
- njengesixhobo sokuthintela ukuvuvukala okanye ukuxhatshazwa emva kokusebenza kwimizimba yesisu kunye nesisu.
Akuyena wonke umntu owaziyo ukuba iFtalazol ingasetyenziselwa emva kokushiya ukutya okuqinileyo okanye ukuzila ukudla ngokunyanzeliswa kwemisebenzi yesigca esiswini. Inceda ngokunyaniseka. Nangona kunjalo, ukuqheleka kubonisa ukuba phthalazole idlalwa ngokukhawuleza ukuba ihudo.
Indlela yokuthatha iipilisi zeFtalazol?
Iibhulethi zeFtalazol ziginya ngokupheleleyo, zihlanjwe ngeglasi yamanzi. Kunoko, inokuhlamba isisombululo se-alkaline, esilula ukuzilungiselela. Ukwenza oku, kongeza iigramu ze-baking soda kwiglasi yamanzi uze udibanise uze udibaniswe ngokupheleleyo. Ukongezelela, kuyacetyiswa ukuba uphuze amanzi amaninzi ngemini, ngokukodwa ngorhudo olunamandla.
Unyango nge phthalazole kufuneka lwenziwe kwiikhosi. Iskimu sokwamkelwa kwekhosi yokuqala (ngesimo esifanelekileyo sesifo) sisilandela:
- Kwiintsuku zokuqala neyesibini kwekhosi yepilisi kufuneka uthathe iziqwenga ezimbini (1 g) nganye iiyure ezine (kuphela 6 g ngosuku);
- Kwiintsuku ezimbini ezilandelayo - ezimbini iipilisi nganye iiyure ezintandathu (kuphela 4 g ngosuku);
- intsuku yesihlanu ukuya kweyesithandathu - ngenani elifanayo lamathebulethi nganye iiyure ezisibhozo (kuphela 3 g ngosuku).
Ikhosi yesibini kufuneka iqhutywe kwiintsuku ezintlanu ukuya kwi sixhenxe emva kokuqala. Iskimu sokuthatha iziyobisi ngolu hlobo lulandelayo:
- Kwiintsuku ezimbini zokuqala, thabatha iipilisi ezimbini ngeeyure ezine, ngobusuku - emva kweeyure ezisibhozo (5 g ngosuku ngamacwecwe 10);
- ngosuku lwesithathu nolwesine - iipilisi ezimbini ngeeyure ezine (kuphela 4 g iipilisi ezi-8);
- ngosuku lwesihlanu, thabatha amaxabiso amathathu ahlukeneyo amacwecwe amabini emva kweeyure ezine (3 g ewonke).
I-dose epheleleyo yekhosi yesibili i-21 grams, kodwa ngokuhamba lula kulula ukunciphisa ama-18 amagremu.
Ukungqinelana nokusetyenziswa kwe phthalazole
Njengazo zonke iziyobisi, iipilisi zeFtalazol zinemiqathango engqinelanayo:
- ukuqonda okuphezulu (okanye ukungabikho komfutho) kumacandelo ekuqulunqweni;
- i-hepatitis ifom elula;
- i-colitis kwifom elula;
- Isifo seBazedov-Graves (i-goiter enobuhlungu);
- umsebenzi ongenakunqwenela umonakalo kwiifom zombini ezingapheliyo;
- glomerulonephritis;
- izifo zesistim ejikelezayo;
- isithintelo esiswini;
- ukuba esikhathini esidlulileyo kukho ukunyuka kwenyameko kwi-sulfonamide;
- khulelwa.