Kukho iintlobo ezahlukahlukeneyo ze-vasculitis, phakathi kwazo apho kukho i-cell cell temporal okanye i-arteritis ye-temporal (GTA). Elinye igama le-pathology isifo sikaHorton, ngokuhlonipha ugqirha owamchaza kuqala.
Esi sifo sifumaneka kakhulu kwi-asebekhulile, sichaphazela imirhoxo yobukhulu kunye nobukhulu obukhulu. Kwiindonga zabo, inkqubo yokuvuvukala iqhubela phambili, eqhubeka isasazeka. Ngexesha elide, iimpahla ezincinci malunga nemvelaphi yokubunjwa kwe-thrombi kwaye kukho iziphazamiso ezahlukahlukeneyo ezijikelezayo.
Izibonakaliso zezifo zeHorton
I-pathology echazwe ngokugqithisileyo iqala ngokugqithiseleyo okanye ingabandezeli, ihlala ikhula emva kokutshintshwa kwentsholongwane yentsholongwane yokuphefumula. Impawu zokuqala ze-GTA:
- intloko;
- myalgia;
- umkhuhlane;
- ubunzima bokuhamba kwemisipha kunye nolwimi.
Iimpawu eziphambili ze-arteritis zesikhashana ziquka iintlobo ezi-3 zeembonakaliso zeklinikhi:
1. Utywala:
- bushushu;
- i-anorexia;
- i-rheumatic polymyalgia ;
- intloko;
- ukukhathala;
- intlungu xa uhlafuna.
Iziphazamiso ze-Vascular:
- Iimodyuli kwesikhumba se-scalp;
- ukudibanisa kweetriyari zeparietal kunye nexesha lexesha;
- ubuhlungu xa kuthengiswa iinqanawa ezilimele.
3. Ukutshatyalaliswa kwamalungu azibonayo:
- kuncitshiswe ubunono obubonakalayo, kwaze kwaba lula ukuphosa ngokukhawuleza;
- i-nechemicic neuropathy ye-optic nererve.
Ukugqithiswa kwemisebenzi yamehlo ayifumanekanga ngokukhawuleza, kodwa emva kweveki ezi-2-4 okanye eziliqela ukusuka ekuqaleni ukuphuhliswa kwezilwanyana, nje ngokuxolelwa kwesifo sikaHorton. Olu tshintsho aluvumelekanga, ngoko ke kubalulekile kuzo zonke izigulane ezine-GTA ukuba zihlolisise rhoqo imeko ye-fundus.
Ukuhlolwa kwegazi kwiSifo sikaHorton
Isiseko sokuxilongwa sisifo esipheleleyo sokuhlolwa kwegazi. Kule miphumo yolu hlalutyo, ezi zilandelayo zichazwe:
- i-hypoemromic anemia ;
- ESR ngaphezu kwama-50 mm / h;
- leukocytosis;
- ukwandiswa komsebenzi weezyme ze-hepatic;
- i-hypoalbuminemia;
- ukwandiswa kwamazinga e-IgG (ngamanye amaxesha).
Ukunyangwa kweempawu kunye nezizathu zesifo sikaHorton
Indlela kuphela efanelekileyo yokwelapha ukuvuvukala kweendonga ze-vascular kunye ne-GTA kukusetyenziswa kwe-horticone ye-corticosteroid, ngakumbi iPrednisolone. Kwiimeko ezinzima, i-regimen yonyango incediswa enye iyeza, iMeprednisolone.
Inkqubo yokwelapha iqhubeka, emva kokuncediswa kwenkqubo yokuvuvukala ecebisayo kucetyiswa ukuba athathe amachiza kwenye iinyanga ezintandathu kwi-dosage yesondlo. Ngaphandle kokungabikho kweempawu ze-Horton's syndrome kwiinyanga ezili-6, unyango luye lwaphela.