I-Mildronate ngumkhiqizo wezokwelapha ophucula umzimba kunye nokukhuthaza ukunikezelwa kwamandla kwezicubu. Kukho iindlela ezimbini zokukhululwa: iipsulules kunye nesisombululo se-injections kwi-ampoules.
Indlela yokusebenzisa i-mildronate ixhomekeke kwisifo kunye nobunzima bayo. Isilwanyana senziwa ngomlomo, nge-intravenously, nge-intramuscularly and parabulbarically (ngaphakathi kwiso).
Indlela yokwenza i-Mildronate yesenzo
Inkqubo yesenzo se-Mildronate kukubonelela ngokukhusela nokunikezelwa kwamanzi ngamaseli ahlukeneyo omzimba. Kwakhona, isichengisi sivimbela ukuqokelela kweemveliso ezinobungozi eziphakathi komzimba, okhusela iiseli kumonakalo. Ukongezelela, i-mildronate iyanciphisa izinga le-oxidation yamacids e-fatty, okwenza kube lula ukusebenzisa enye indlela yamandla. Ingundoqo yale nkqubo i-oxidation ye-glucose, kwaye i-glucose iyaziwa ukusebenzisa i-oksijini ngokufanelekileyo ngokuchanekileyo kwe-adenosine triphosphate (ATP).
Ukulungiswa kweMildronate: izibonakaliso zokusetyenziswa
Uluhlu lwezifo apho i-mildronate imiselwe khona kakhulu, ezi ziphambili zi:
- ukuhluleka kwentliziyo engapheliyo;
- i-angina pectoris, i- myocardial infarction , ischemic disease;
- isifo sikashukela, i-osteochondrosis yommandla wesibeleko, kunye nayiphi na imeko apho ukujikeleza kwegazi kwintliziyo kuphazamiseka;
- kunye noxwala - i-withdrawal syndrome;
- ukuncipha kobuchule;
- ukuxhomekeka kwimeko yengqondo nangokwenyama, umzekelo, kwiimbaleki;
- kwonyango lweentlobo ngokubambisana nezinye iziyobisi;
- i-cardiomyopathy, ngenxa yeengxaki ze-hormonal (ukusetyenziswa kwexesha elide le-prednisolone, ukuyeka umyeni)
- ukubola kwamanzi kwi-retina yelihlo.
Uluhlu olupheleleyo lwezibonakaliso lufakwe kwisichasiselo kwisiza.
Kanye kunye nobungqina, kufuneka utsho amagama ambalwa malunga nokuchasene. Ezi ziquka:
- ukungahambi kakuhle kweziyobisi kunye nezixhobo zayo;
- uxinzelelo olusandayo;
- izibilini ezingenayo;
- ukuphulwa kwegazi eliqhelekileyo legazi eliphuma emzimbeni.
I-Mildronate kubadlali
Ngenxa yeepropati ezinikezelwa ngumkhiqizo, zisetyenziswa kakhulu kwimidlalo.
I-Mildronate ngempumelelo ikunceda ukujamelana nabagijimi abaneemithwalo, ngamanye amaxesha angavumeleki, zombini kunye nengqondo. Esi siphumo siphumelele kwixabiso lomzimba wokusebenzisa izibonelelo zalo zendalo ngokubanzi. Okokuthi, umphumo we-pesronate yezilwanyana ijoliswe ekuqinisekiseni ukuba umzimba unako, ngokukhawuleza kwaye unokukhawuleza ulungelelanise nezimo ezixinzelelekileyo, eziyimithwalo engokwenyama, yengqondo nengqondo.
Ukongezelela ukulungelelanisa, i-Mildronate nayo inegalelo ekuphuculeni ngokukhawuleza, ngoko abameli beemidlalo ezahlukeneyo kunye nezohlukeneyo baye basebenzisa eli liyeza kwinqanaba lokulungiselela nokukhuphisana.
Kwabadlali, indlela efanelekileyo kakhulu yokuthatha i-mildronate i-15-20 mg yesilwanyana nganye ngeekhigram yesisindo isigqithi seyure ngaphambi koqeqesho. Ubude bekhosi buvela kwi-1.5 ukuya kwiinyanga ezi-3, emva koko uthathe ikhefu, ukwenzela ukuba ungaphucanga ukuphumelela kwonyango.
I-Mildronate ayiyonto yokutshatyalaliswa kwezinto, njengoko ingakhuphukiyo
I-Mildronate yokulahleka kwesisindo
I-Mildronate i-analog ye-carnitine kwaye iphucula kakhulu inkqubo ye-metabolic. Thetha malunga neziyobisi njengeendlela ezizimeleyo zokulahlekelwa kwesisindo akudingekile. Inxaxheba yakhe ekunciphiseni ubunzima kubangelwa ukuphucula ukusebenza kwezemidlalo kunye nokulungelelaniswa ngokukhawuleza kumthwalo. Oko kukuthi, ukusebenzisa i-mildronate kunokunciphisa umzimba, kodwa kuphela ngexesha lokuzikhandla ngokomzimba.