I-Glycated (okanye i-glycosylated, i-HbA1c) i-hemoglobin iyisalathisi yezinto eziphilayo ezibonisa izinga leshukela legazi kwiinyanga ezintathu zokugqibela. I-Hemoglobin yiprotheyini equlethwe ngamaseli obomvu. Ngokubambisa ixesha elide kwiiprotheni ezinjalo, bayazibophelela kwi-compound ebizwa ngokuba yi-hemoglobin ene-glycated.
Qinisekisa i-hemoglobin ene-glycated njengepesenti ye-hemoglobin epheleleyo egazini. Ephakamileyo izinga leswekile, i-hemoglobin ngaphezulu, ngokulandelanayo, iya kubanjwa, kwaye iphakamileyo le xabiso. Futhi ekuqwalaseleni ukuba i-hemoglobin ayibopheli kanye kanye, uhlalutyo alubonakali kwinqanaba leshukela legazi okwangoku, kodwa lixabiso eliqhelekileyo kwiinyanga eziliqela, kwaye enye yeendlela eziqhelekileyo zokufumanisa i-diabetes nesimo sesandulela ngentsholongwane.
Isiqhelo se-hemoglobin ene-glycated egazini
Uluhlu oluqhelekileyo lomntu onempilo lubonwa njengoluhlu lwe-4 ukuya ku-6%, ama-indices avela kwi-6.5 ukuya ku-7.5% angabonisa isongelo sokuhlakulela isifo sikashukela okanye ukusilela kwintsimbi emzimbeni, kwaye amanqaku angaphezu kwe-7.5% ngokuqhelekileyo ibonisa ukuba khona kwesifo sikashukela .
Njengoko kunokubonwa, ixabiso eliqhelekileyo le-hemoglobin eline-glycated zihlala ziphakamileyo kuneendlela eziqhelekileyo zokuhlalutya ngokuqhelekileyo ngegazi (3.3 ukuya ku-5.5 mmol / L ngokuzila ukudla). Oku kubangelwa ukuba i-blood level yeglucose kunoma yimuphi umntu uguquka kulo lonke usuku, kwaye emva kokutya kunokufikelela kuma-7.3-7.8 mmol / l, kwaye ngokuphakathi kweeyure ezingama-24 umntu onempilo kufuneka ahlale ngaphakathi 3.9-6.9 mmol / l.
Ngaloo ndlela, i-hemoglobin index ye-4% ihambelana neshukela legazi elingama-3.9, kunye ne-6.5% ukuya kwi-7.2 mmol / l. Kwizigulane ezinezinga elifanayo lentetho yeshukela legazi, i-hemoglobin ye-glycated index iyahluka, ifike kwi-1%. Ukungafani okunjalo kubakho ngenxa yokuba ukubunjwa kwesi sichazi sezinto eziphilayo kungathonyelwa zizifo, uxinzelelo, ukungabikho kwamacronutrients athile (ngokukodwa isinyithi) emzimbeni. Kubasetyhini, ukuphambuka kwe-hemoglobin e-glycated kwizinto eziqhelekileyo kunokuvela ekukhulelweni, ngenxa ye-anemia okanye isifo seswekile somama.
Indlela yokunciphisa umgangatho we-hemoglobin e-glycated?
Ukuba izinga le-hemoglobin enyunyiweyo linyuka, le nto ibonisa isifo esibi okanye ithuba lokuphuhliswa kwayo. Ngokuqhelekileyo kukho imeko yesifo sikashukela, apho izinga eliphezulu lezeshukela legazi ligcinwa rhoqo. Ngaphantsi kaninzi - ukungabi ncitshi emzimbeni kunye negazi legazi.
Ubomi bemizimba yegazi ebomvu malunga neenyanga ezintathu, le sizathu sokuba ixesha lokuhlaziywa kwe-hemoglobin elineglycated ibonisa izinga eliphakathi kweeshukela egazini. Ngaloo ndlela, i-hemoglobin ene-glycated ayibonakali yohlukwano olulodwa kwizinga leshukela legazi, kodwa libonisa umfanekiso oqhelekileyo kwaye inceda ukugqiba ukuba izinga leetyhukela legazi lidlulileyo
Ukuqhelanisa lesi sikhombisi, kufuneka uholele indlela yokuphila enempilo, landela ukutya okumiselweyo, uthathe imithi enqunyiwe okanye wenze ii- insulin kunye nokujonga i-sugar levels.
Ngesifo sikashukela, isantya se-hemoglobin esine-glycated esiphezulu kunabantu abanempilo, kwaye inani livunyelwe ukuya kuma-7%. Ukuba isibonakaliso sidlula i-7% ngenxa yoluhlalutyo, oku kubonisa ukuba isifo sikashukela asihlawulwanga, oko kungakhokelela ekuphuhlisweni kweengxaki ezinzulu.