Ngokuphindaphindiweyo emva kokufumana iziphumo zokuhlalutya kwegazi legazi, isiguli sifunde ukuba uye wenyuka i-bilirubin iyonke - oko kuthetha ukuba kuphela ukucacisa inani elipheleleyo alikho. Inyani kukuba i-concentration ye-pigment iyi-set of indicators of bilirubin ngokuthe ngqo. Yiyo le miphumo eyenza ukwazi ukufumana ukuba yeyiphi indlela yokulahleka kwendalo, kwaye yintoni isizathu sokuphambuka kohlalutyo oluqhelekileyo.
Kutheni i-bilirubin jikelele ingakhutshwa kwi-test test?
Yonke into eyenza ukugqithisa ubuninzi bexabiso eliqhelekileyo le-bilirubin lihlelwe ngezigaba ezine. Ukwahlukana kusekelwe kwiinqanaba zokutshintshisiswa kwezinto ezinokubaluleka, kunye ne-2 echaza imigaqo:
- Ubume bendawo ebangela ukuba i-pigment yellow-green pigment ikhuphuke (esesibindi okanye ngaphandle kweli candelo).
- Indlela yokwandisa i-bilirubin (ngqo okanye engaqondanga).
Ngokwale ndlela yokuhlukanisa, ezi zizathu zezizathu zokunyusa inani le-pigment ephuzi eliluhlaza zihluke:
- Ukuphakama kwe-Hepatic ye-bilirubin-kwiiseli zesibindi, ukuveliswa kwe-bile kuphazamiseka, ngenxa yoko ukuphuma kwayo kuhlahloke ngokuthe ngqo kwi-bin ducts ngaphakathi kwesibindi.
- Ukwanda kwe-extrahepatic ye-bilirubin-outflow ye-bile iphazamiseka kwiidoksi ze-extrahepatic.
- Ukuphakama kwe-hepatic ye-bilirubin yamahhala-kwiiseli zesibindi kukho ukuguqulwa okungalunganga kwe-pigment yamahhala ibe ifom ngqo.
- Ukwanda kwe-extrahepatic kwi-bilirubin yamahhala-ngaphandle kwesibindi, i-pigment yellow-green pigment ezamahala.
Ngamanye ala maqela aneempawu zokubonakaliswa kwekliniki, ngenxa yokuba kunokwenzeka ukuba ubeke ukuxilongwa kwangaphambili.
Kubalulekile ukuba uqaphele ukuba nangona i-bilirubin iyonke yanda, uphando oluninzi lufunekayo. Kubalulekile nje ukuba isibonakaliso senani lemali eboshwe kunye ne-pigment ezamahala.
Yintoni eyongeziweyo i-bilirubin egazini kunye nokwanda kweqhekeza ngqo?
Izifo ezihambelanayo nemeko echazweyo ingaba yi-intrahepatic and extrahepatic.
Iqela lokuqala liquka:
- hepatitis:
- i-viral viral;
- ibhaktheriya;
- engapheliyo;
- mayeza;
- inetyhefu;
- ngokuzenzekelayo;
- izibilini zesibindi;
- cholestasis intrahepatic;
- i-cirrhosis eyimfuneko yebhiliyari;
- i-jaundice yabasetyhini abakhulelweyo;
- I-Rotor syndrome;
- I-Dabin-Johnson syndrome.
Iqela lesibini liqukethe izifo:
- i-pancreatitis enobuhlungu kwaye engapheliyo;
- ichinococcosis yesibindi ;
- aneurysm yeerpiyiti;
- i-diverticulitis ye-duodenum;
- isifo se-pancreas;
- i-cholangitis engapheliyo, ekhulayo kunye neyodwa;
- cholelithiasis;
- ukuvuvukala kwe-duodenum;
- i-neoplasm kwi-bile duct.
Ukunyuka kwe-bilirubin epheleleyo kunye neempawu zonyuka kwi-pigment engqalileyo-ithetha ntoni?
Ukuba i-concentrations ye-bilirubin yamahhala yonyuka kunye nokwanda kwangexesha elifanayo kwixabiso le-pigment, izizathu zingaphunyezwa zombini ngaphakathi kwimizimba yesibindi nangaphandle kwayo.
Kwimeko yokuqala, kukho izifo ezinjalo:
- i-Kriegler-Nayyar syndrome;
- fumana i-hemolytic jaundice;
- Isifo sikaGilbert;
- I-Lucy-Driscola syndrome.
Izifo ze-extrahepatic ziquka:
- ufumane i-hemolytic anemia, ngokuqhelekileyo kwimvelaphi eyimimandla;
- i-hemolytic anemia yokuzalwa
- sepsis ;
- i-hemolysis ye-erythrocyte kwiintsana;
- malariya;
- i-hemolytic anemia;
- i-hemolytic anemia.