Amanqanaba aphezulu e-cholesterol egazini ayingozi kwimpilo. Kodwa unokuhlangabezana nale ngxaki ngokusebenzisa izidakamizwa ezizodwa: i-statins kunye ne-fibrates. Zichaphazela iinkqubo ezahlukeneyo ze-biochemical ezenzeka nje kuphela kwimveliso ye-cholesterol, kodwa nakwiinguqu zayo kumzimba womntu.
Izitatimende zokunciphisa i-cholesterol
Iitatimins zezidakamizwa ezithandwayo zanamhlanje zinciphisa i-cholesterol egazini. Ngoku kunene banceda ngokukhawuleza, kuba umgaqo wabo wesenzo usekelwe ekukhutshweni kwe-enzyme, esesibindi kunye noxanduva lokuvelisa i-cholesterol. Enye yeemimiselo eziqhelekileyo ezichanekileyo, ezikhuselekileyo nezisebenzayo nguSimvastatin. Impembelelo yokwelapha yeso siphumo ikhula ngaphakathi kweentsuku ezili-14 emva kokuqala kokonyango. Kodwa emva kokugqitywa kweyeza, inqanaba le-cholesterol liza kubuyela kwinqanaba langaphambili. I-Simvastatin ayinakuphikiswa. Ezi macwecwe zingasetyenziselwa njengendlela yokukhusela izigulane ezinezonyango zomzimba okanye isifo sikashukela esikukhusela ukuphuhliswa kweengxaki ezahlukeneyo zentliziyo.
Iziyobisi ezinciphisa i-cholesterol egazini, ziquka i-Atorvastatin. Ezi macwecwe zihlala zichazwe kwezi gulane ezingenayo impendulo eyaneleyo ekudleni kunye nezinye iindlela ezingenalo unyango. I-Atorvastatin inciphisa kakhulu umngcipheko:
- uphuhliso lwe-stroke kunye ne-angina pectoris;
- Ukufa kwisifo se-ischemic ;
- ukwenza umsebenzi we-revascularization.
Sebenzisa ukucutha ngokukhawuleza i-cholesterol, kunye nokuthintela ukuphuhliswa kwe-atherosclerosis kunye ne Pravastatin. Ezi pilisi ziphumelela ngokwenene, kodwa ngaphambi nangesikhathi kunyango, kunyanzelekile ukuba kugcinwe ukutya okukhethekileyo kwe-cholesterol. I-Atorvastatin kunye nePravastatin zizidakamizwa ze-statin ezinciphisa i-cholesterol egazini, ezingenakuthatyathwa ngezifo zesisu zomzimba, izifo ezahlukahlukeneyo zesibindi (ikakhulukazi kwisigaba esisebenzayo) kunye nokukhulelwa.
I-Fibrate yokunciphisa i-cholesterol
Iitatimins zithinta i-cholesterol ephantsi. Kuthekani ukuba ubuninzi bayo buninzi ngokwaneleyo? Ziziphi iziyobisi ezinciphisa i-cholesterol egazini kwimeko? AmaFibrate aya kukunceda. Ezi ziipilisi ezichaphazela i-lipid metabolism. Iilwimi ezingcono kakhulu ezinciphisa i-cholesterol egazini nakwizinga eliphezulu kakhulu:
- Bezafibrate;
- Phrofibrate;
- Gemfibrozil;
- Fenofibrate.