Umsebenzi we-cardiovascular system uhlolwe ngokulinganisa uxinzelelo lwegazi. Ngeempembelelo ezahlukeneyo zalolu lathisi, isilwanyana seCaptopril simiselwe. Kwi-cardiology isetyenziswe kaninzi, kwaye nangona isiseko sezifundo zonyango elide.
Nangona ukuxhaphaka kweli galelo kuninzi, akubona zonke izigulane ziyazi ukuba uxinzelelo ukuthatha iCaptopril kunye nendlela esebenza ngayo emzimbeni.
Iyancipha okanye yandisa uxinzelelo lweCaptopril?
Isiza esicacisiwe siphuhliswe kwisiseko senkunkuma esebenzayo yegama elinye. Uhlanganiswe kwiqela le-ATP-angiotensin eguqulela i-enzyme inhibitors. Oku kuthetha ukuba i-captopril inqanda ukubunjwa kwezinto ezizodwa ezibangela ukunciphisa kwe-lumen yemithwalo yegazi. Ngelo xesha, isithako esisebenzayo sikhuthaza ukuqokelela kwe-bradykinin. Le enzyme iyandisa i-vascular gleams.
Ngaloo ndlela, le nkunkuma inemiphumo echasayo, kwaye kulula ukuqiqa ukuba yintoni uxinzelelo lobungozi bokuthatha uCaptopril - ukwanda. Ngaphezu koko, iyeza livelisa iziphumo ezilandelayo:
- Ukuphucula ukunyamezela kweentliziyo zomzimba kumthwalo;
- ukunciphisa ukuxhatshazwa kwemida yegazi kwigazi;
- ukwanda kwenkunzi kunye nokuhamba kwegazi;
- kuncipha kwi-intensity ye-aldosterone yokuvelisa kwiingqungquthela ze-adrenal;
- ukwanda kwimizuzu emininzi yentliziyo;
- ukunciphisa uxinzelelo lwegazi kwindawo ye-aortiki;
- ukujongwa kwemimiselo yexinzelelo yokutshata kwi-pulmonary (encinci) isangqa sokujikeleza kwegazi kunye ne-atrium efanelekileyo;
- ukunciphisa ukuhlanganiswa kweplatelet .
Ngokusetyenziswa kwexesha elide kweziyobisi, ukunikezelwa kwegazi kwi-myocardium kuphucula phantsi kweemeko zeenkqubo ezingapheliyo, i-hypertrophy, kunye nokunyuka kwengqondo kwiindonga zeetriyiti zoluhlobo olusasahlayo, luyehla.
Yiyiphi inqanaba lexinzelelo eliphezulu legazi eliza kunceda amaphilisi e-capsopril?
Isiza esicetywayo sisoloko sinyulwa ukuba silungiselele iikholeji zangexesha elide okanye ezizeleyo zonyango kunye nolondolozo lwamayeza.
Isilwanyana sisona siphumelele kwisifo esixinzelelekileyo sezinga elincinci ukuya kumodareyitha, xa iinkozo zeetonometer zingadluli kwi-179 nge-109 mm Hg. Ubugcisa. Kule meko, iziyobisi zingasetyenziswa kwaye njenge-monotherapy enezithintelo zokungenisa izakhi ze-sodium emzimbeni.
Ukusetyenziswa kwe-captopril kwixinzelelo olunyuke kakhulu, ngaphezu kwe-180 kwi-110 mm Hg. kufuneka ukuba idibaniswe nokulawulwa kwe-thiazide diuretics (i-diuretics). Umlinganiselo wesirya osisiseko ukhula kancinci uze ufinyelele kwi-concentration evumelekileyo - 150 mg yesithako esisebenzayo ngosuku.
Kungatsholwa ukuba le nkunkuma inceda kunoma yiphina ingcinezelo eyongeziweyo, ngokukodwa ngokudibanisa neziyobisi ezincedisayo.
Kukuphi uxinzelelo olubonisa ukusetyenziswa kweCaptopril?
Ngenxa yeengongoma ezingentla apha, le myeza ekhuselekileyo isilungele kokubili kunye nocwangcisekileyo, kwaye
Ukongeza kwesi sifo, i-captopril ibonakaliswe kunyango lwezilwanyana ezilandelayo:
- i-infyoction ye-myocardial ne-left ventricular dysfunction, ukuba imeko yesigulane izinzile;
- Uxinzelelo lwengqondo
- ukuhluleka kwentliziyo (ingxaki yokudibanisa idibeneyo);
- isifo sikashukela se-1 esine-nephropathy yesifo sikashukela, ukuba izinga le-albuminuria lingaphantsi kwe-30 mg / ngosuku;
- i-cardiomyopathy yemvelaphi eyahlukeneyo.