Ngabe iirmone zonyango zokutshintshwa zihlala ziqala nini?
Njengoko kuyaziwa, ukuqala kwexesha lokunyuka kwimizimba emzimbeni wesibini kunqunywe i-genetically, i.e. ukuphela komsebenzi wokuzala akukwenzeka ngexesha elifanayo kwabesetyhini abahlukeneyo. Kucaciswa ukuba ngababameli belizwe laseYurophu eli xesha liwela kwi-45-55 iminyaka. Kule meko, ukuphakama kokunyuka komzimba kubonakala kwiminyaka engama-50.
Yona ndlela yokuguga kwezesondo, ii-ovaries, ziqala ngokukhawuleza, emva kweminyaka engama-35. Ukukhawuleza kubonakala xa ibhinqa liwela umgca kwiminyaka engama-40.
Ngokusekelwe kulo mbandela, umzimba wesetyhini udinga inkxaso ye-hormonal emva kweminyaka engama-50. Kule meko, yonke into ixhomekeke kubukhulu beempawu zokumelana nokuphuma kwesisu.
Ziziphi iziyobisi ezisetyenziselwa ukuqhuba unyango lwe-hormone ye-menopausal?
Ukuzalisekisa olu hlobo lonyango ngokuqhubekayo, kusetyenziswa izigulane zendalo kuphela. Phakathi kwazo kunokuthiwa yi-Estron, Estriol.
Ukususela kumalungiselelo aqukethe i-estradiol ekusebenzeni kwawo, sebenzisa i-Estradiol valerate okanye i-17b-estradiol.
Iigestagens zisetyenzisiwe kumancinci amancinci kakhulu, anikezela ngolo hlobo okuthiwa yi-secretory transformation ye-endometrium (utshintshe kwisalathisi sangaphakathi sesisu). Ngexesha elifanayo bathathwa kunye ne-estrogen ngeentsuku ezi-10-12.
Ukunyanga okunzima kwengxaki ye-climacteric syndrome kubandakanyeka kubandakanya iziyobisi ezingabandakanyi ukuphuhliswa kwe-osteopenia (isifo esihamba kunye nokuphulwa kwethambo loxinzelelo). Njengezobisi, iipilisi ze-calcium ezinokusetyenziswa.
Unyango lwolu hlobo lubekwe imiqondiso ethile, kunye nesifo se- climacteric syndrome, umzekelo. Xa uqhuba unyango lwe-hormone ye-menopausal, ibhinqa kufuneka ihambelane neengcebiso zekliniki ezinikezelwa ngugqirha, apho unyango lwenziwe kulo lonke ihlabathi.