Umzimba womntu uyinto eyingqayizivele, eyinkimbinkimbi kakhulu. Nangona i-anti-history yamachiza, kude kube ngoku, zonke izixhobo kunye nobuchule bomzimba womntu azifundanga kakuhle. IHormones yenye yeendlela ezinamandla kakhulu zokuzilawula umzimba, kwaye kule nqaku siza kuthetha ngenye yazo - androstenedione. Ngokuchanekileyo, malunga nento eboniswe lizinga eliphezulu le-androstenedione, indlela yokunciphisa i-androstenedione, nokuba ngaba kuyimfuneko ukuba ukhathazeke ukuba iimvavanyo zelabhorari zibonise ukuba i-hormone ne -rostenedione iphakanyisiwe kuwe.
Yintoni na iAndrostenedione inoxanduva?
I-Androstenedione yi-hormone ye-adrenals kunye ne-gonads. Iveliswa emzimbeni wamadoda nabasetyhini. Ukuxhomekeka ngokungenakuqhathaniswa nokuphuhliswa kwamahomoni eesini zesini kunye namadoda, ikakhulukazi i-estrogen kunye ne testosterone. Inani elaneleyo le hormone egazini livumela ukuba izicubu zesibindi kunye namafutha avelise ngokunyanisekileyo ukuvelisa i-hormone yesondo.
I nqanaba le-androstenedione liqala ukunyuka ngokukhawuleza ukusuka kwiminyaka eyi-7-8. Emva kokufikelela kumntu oneminyaka engama-30 ubudala, ukuphuhliswa kwe-hormone kuqala ukuhla kwehla.
Androstenedione: isiqhelo kubafazi kunye namadoda
Inqanaba eliqhelekileyo le-androstenedione egazini, kuxhomekeke kwiminyaka yomntu:
- abantwana 1-7 emva kokuzalwa - 20-290 ng / 100ml;
- Iintsana (iinyanga ezi-1-12) - 6-68 ng / 100ml;
- abantwana abaneminyaka eyi-1-10 iminyaka-8-50 ng / 100ml;
- abaselula (10-17 iminyaka) - 8-240 ng / 100ml;
- amadoda - 75-205 ng / 100ml;
- abafazi - 85-275 ng / 100ml.
Ukuphambuka okuphawulwayo ukusuka kwinqanaba eliqhelekileyo le-androstenedione liyakubonwa ngokungeniswa kweziyobisi ze-hormonal, izicubu zeendlela ezihlukeneyo kunye nezifo ezininzi.
Androstenedion ephakanyisiwe: izizathu
Izizathu zokunyuka kwamazinga a-androstenedione ingaba yintlupheko kumsebenzi we-adrenal kunye / okanye we-ovarian. Ngokuqhelekileyo, ukwanda kwinqanaba le-androstenedione kubonisa ezi zifo:
- ovary polycystic;
- hyperplasia ye-correnx ye-adrenal;
- I-Itenko-Cushing syndrome;
- osteoporosis;
- i-hypertecosis ye-oromes;
- izicubu ze-ovari zendalo ezahlukahlukeneyo kunye nezinye izifo.
Inqanaba elinciphileyo le-androstenedione liyabonwa ngokungabikho kwamaqanda okanye i-corrox ye-adrenal.
Ngokuxhomekeke kwithuba lemihla, isigaba somjikelezo wokuya esikhathini, i-androstendione level ihluke. Amazinga aphezulu ayafunyanwa ngehora langentsasa, kwaye phakathi kwimijikelezo yokuya esikhathini kubafazi. Ngexesha lokukhulelwa, izinga le hormone landa.
Androstenedione ephakamileyo: iimpawu
Ukuba i-androstenedione kubasetyhini iphakanyisiwe, ngokuqhelekileyo kukho ukulahleka kweenwele ezigqithiseleyo (i-hirututism), ukulungisa i-syndrome. Ukwanda kwinqanaba le hormone kunokubangela ukuba ufikelele ekukhuleni, ukuphuma kwegazi, iintlobo ezahlukahlukeneyo zokungasebenzi kwimisebenzi yokuzala yomzimba ngokusesikweni kokungalingani kwe-hormone jikelele.
Kukholelwa ukuba ukwanda kwe-androstenedione kukhokelela ekunyuseni ngokukhawuleza kwimizimba ye-muscle, yingakho le hormone kunye nezilungiselelo eziqulethwe ziyaziwa kakhulu phakathi kwabakhi bomzimba, nangona ayinayo impembelelo ye-anabolic. Okwangoku, inkohlakalo ekusebenziseni okungalawulwayo kwezidakamizwa ngamanye amaxesha angaphezu kwefuthe elihle lokusetyenziswa kwalo-ukukhahlela, ukukhulisa iprotate, ukuphulwa kwamanani emzimbeni (umzekelo, ukukhula kwebele kumadoda), iinwele ezithinteleyo emzimbeni-okude kuluhlu olupheleleyo lweempembelelo zalo ukumkelwa okungalawulwayo.
Androstenedione ephakamileyo: unyango
Ukuba izinga le-androstenedione liphakanyisiwe kwabasetyhini, kufuneka ukuba unyango lufuneka. Ukuxilonga nokunika unyango olwaneleyo, kufuneka uqhagamshelane ne-endocrinologist kunye ne-gynecologist (kubafazi) okanye i-androlog (yamadoda).
Into esetyenziswa ngokuqhelekileyo: i-dexamethasone, i-clomiphene, i-contraceptive ezahlukeneyo ze-hormonal. Iirejimeni zonyango, uluhlu lwezilwanyana kunye neendlela zokwelapha ziyahluka kakhulu kuxhomekeke kwizizathu kunye nobume beengxaki, ubukho bezifo ezidibeneyo, ubudala kunye nesimo esiqhelekileyo sesigulane. Ukuzizinyameka kuyacinywa. Zonke iziyobisi ze-hormone mazimiselwe kuphela ngumcali oqeqeshiwe.