Warfarin anogues

I-Warfarin yipilisi edala kunayo yonke iqela elivela kwiqela le- anticoagulants , ngokugqithiseleyo kunobuthi kwaye lifuna ukubeka esweni rhoqo izikhombisi zegazi. Kuze kube yimhla, kukho iifanethi zanamhlanje zeWarfarin ezineempembelelo ezimbalwa, phakathi kwazo ezona zinomdla kakhulu ezinokuthathwa ngaphandle kokubeka esweni rhoqo i-INR (isalathisi esichaza i-coagulability yegazi).

IWaffarin yaManalog

IMarfarex

Iipilisi ezine-1.3 okanye 5 mg yesithako esisebenzayo (i-wardium ye-sodium). Zifakwe kwi:

• thromboembolism yemiphunga;
• thongsis;
• ukuhlasela kwentliziyo;
• iiprothethethi zeentsimbi zentliziyo.

Marewan

Iipilisi ezine-3 mg ye-warfarin ye-sodium. Zifakwe kwi:

• thrombosis;
• i-infarction kunye nokuthintelwa kweengxaki emva kokuhlaselwa kwentliziyo;
• ezinye izifo zentliziyo, kuquka i-valve prosthetics;
• unyango kunye nokuthintela imivimbo kunye nokuhlaselwa kwe-ischemic.

Zomibini izidakamizwa, eqinisweni, zifana ne-Warfarin kwaye zihluke kuphela kumxholo wezinto ezincedisayo. Ukubeka iliso kwi-INR kunye nezinye izilumkiso xa zisetyenzisiweyo.

Yintoni enye engayifumana iWarfarin?

Apha siza kuqwalasela amanye amalungiselelo kunye nolu hlobo lwezenzo ezi-antiticoagulants, ngoko ke zingasetyenziswa endaweni ye-Warfarin.

Pradaxa

Isilwanyana sisisithintelo ngqo kwi-thrombin kwaye, sibopha, sivimbela ukubunjwa kwe-thrombi. Isiza sisetyenziswa:

• kunyango kunye nokuthintela i-thrombosis yamalungu;
• ekuthintekeni kwemivimbo , i-systemic thromboembolism;
• ukunciphisa umngcipheko weengxaki kwi-fibrillation ye-atrial.

Xarelto (rivaroxaban)

I-inhibitor ngqo ye-factor Xa (i-coagulation factor, okuyi-prothrombin activator). Isilwanyana sivimbela ukubunjwa kwee-molecule zamanzi kunye neempembelelo ezikhoyo kwigazi. Se tyenziswe ukukhusela:

• i-thromboembolism emva kokusebenza kwamathambo kumalungu angaphantsi;
• imivimbo kunye ne-systemic thromboembolism kwizigulane ezine-fibrillation ye-agriyo.

Yintoni engcono - iPradaksa, Xarelto okanye iWarfarin?

Inzuzo ecacileyo kaPradax, njengo-Xarelto, kukuba le mithi ayifuni ukulawulwa kwe-INR kwaye, xa ithathwa, ingozi encinane yemiphumo emibi. Nangona kunjalo, la mayeza Zisetyenziselwa kuphela iintlobo ze-non-valvular zesifo senhliziyo. Okokuthi, ukuba kukho iiplavishini ezibonakalayo okanye umonakalo we-rheumatic kwiintsimbi zentliziyo, azinqunywanga, ngokungafani neWarfarin.

Xa ukhetha phakathi kwe-Xarelto ne-Pradaksa, kuyafaneleka ukuba sicinge ukuba i-Xarelto ithathwa kuphela kanye ngosuku, kwaye iPradaksa ifuna iindlela ezininzi. Ukongezelela, kukholelwa ukuba i-Xarelto ayikho ingozi kakhulu inokuchaphazela iphepheni yesisu.

Ekubeni zonke ezi ziziyobisi zichaphazela izikhombisi ezibalulekileyo, kukugqirha kugqirha ukucacisa ukuba yiyiphi enye i-warfarin eya kutshintshwa kwaye ingaba iifaneli zayo ziyamkeleka.