I-Digoxin yipilisi esetyenziswa kakhulu kunyango lwezifo zentliziyo, ngokuphindaphindiweyo kwimiqulu yamacwecwe. Uthunyelwa kwiqela le-pharmacological ye-cardiac glycosides - amayeza emfuyo, ane-cardiotonic ne-antiarrhym effect.
Ukwakhiwa kweMikhali kunye nempembelelo yokwelapha kweepilisi zeDigoxin
Isithako esisebenzayo sesilwanyana I-Digoxidine yinto efana ne-digoxidine, ehlukileyo kumagqabi esityalo, i-digitalis woolly. Ezinye izixhobo zefomethi yefayili zi:
- i-silicon dioxide colloidal;
- gelatin;
- i-magnesium stearate;
- talc;
- isitashi ukusuka kwimbombo;
- lactose monohydrate.
Xa uthathwa ngomlomo, isicatshulwa sithathwa kakuhle kwisigxina sesisu kwaye siyasiphumela isiphumo sayo malunga neeyure ezingama-2-3 emva kokungena. Umphumo wokwelapha uhlala ubuncinane kwiiyure ezingama-6. I-remedy ikhutshwe ikakhulukazi ngomchamo.
Ngaphantsi kwempembelelo yento esebenzayo yesilwayo, ezi ziphumo zilandelayo:
- ukwanda kwindlela yamandla e-myocardial miscle (effect inotropic effect);
- ukwanda kwenani lokutshatyalaliswa kwegazi;
- kuncipha kwixesha lezithintelo zeentliziyo zomzimba;
- ukunciphisa umlinganiselo we-systolic nesigxina se-diastolic intliziyo yentliziyo;
- ukunciphisa imfuno ye-oksijeni ye-myocardium;
- isenzo esichaphazelekayo (ngokunciphisa izinga leempembelelo ngokusebenzisa idiodrioticity node kunye nokwandisa ixesha elifanelekileyo le-refractivity);
- impembelelo ye-vasodilator (kunye nokuxinisa kwimvelaphi yentsilelo yeentliziyo );
- siphumo so
- ukunciphisa ukuphefumula;
- kuncipha kwi-edema, njl
Iimpawu zokusetyenziswa kweziyobisi i-Digoxin
Izibonakaliso eziphambili zokusetyenziswa kweyeza I-Digoxin zezi zifo:
- ukuhluleka kwentliziyo engapheliyo yeeklasi ze-II, III kunye ne-IV (njengengxenye yonyango oluyinkimbinkimbi);
- uhlobo lwe-tachycardic ye-fibrillation ye-atrial;
- i-fridayysmal fibrillation ye-atrial;
- i-tachycardia yesahara.
Ukuthotyelwa kwemilinganiselo kunye nokusetyenziswa kwamacwecwe e-Digoxin
Ngokubhekiselele kuwo onke amayeza eqela le-carlyac glycosides, umlinganiselo weDigoxin ukhethwa ngokunyamekileyo ngudokotela oya kwiinkcukacha, ngokuqwalasela iimpawu zomzimba wesigulane, ubunzima kunye nenkqubo yeepathological processes, kunye neeparitha ze-electrocardiogram ze-cardiac.
Ngokomzekelo, enye yeerimi yokuthatha isiza kwifom yefomathi ibandakanya ukuqeshwa kweDigoxin kwisixa se-0.25 mg 4-5 ngamaxesha ngosuku lokuqala kunyango, kwaye kwiintsuku ezilandelayo - 0.25 mg kathathu ngosuku. Kule meko, ukumkelwa kufuneka kwenziwe phantsi kolawulo lwamayeza.
Emva kweempembelelo eziyimfuneko (ngokuqhelekileyo emva kweentsuku ezi-7 ukuya kwezingama-10), i-dosage iyancishiswa, amanyathelo okugcinwa kweziyobisi anqunyelwe ukusetyenziswa kwexesha elide. Ukutyunjwa kwamagciwane angenayo i-intravenous injection, njengomthetho, kuyadingeka kuphela xa kwenzeka ukuhluleka okukhulu kwegazi.
Iimpawu eziphambili zeDigoxin:
- isicefe
- ukuhlanza;
- iziphazamiso zesitopu;
- ukungabi nesidlo;
- intloko;
- ukungcola;
- izifo zokulala;
- ukuhluleka kwentliziyo;
- ukuphuma kwegazi;
- ukubetha;
- urticaria;
- buthathaka;
- ukukhathala, njl
Ukungqinelana nokusetyenziswa kwe-Digoxin:
- utywala kunye ne-cardiac glycosides;
- i-myocardial infarction;
- angina engaqinisekanga ;
- I-Wolff-Parkinson-White syndrome;
- kwibhodi ye-atrioventricular;
- i-bradycardia eneembonakaliso ezinkulu zekliniki;
- isifo senhliziyo esisisigxina;
- mitral stenosis nabanye.