Esinye sezizathu eziqhelekileyo zokungabikho komntwana kungukuxhaswa kwe-hyperandrogenism kubasetyhini -ukugula kwenkqubo ye-endocrine. Olu xilongwe lufunyanwe kwi-20% yabasetyhini.
I-Hyperandrogenism kubasetyhini - ibangela
I-Hyperandrogenia kubafazi ibangelwa zizifo ze-endocrine, kunye nezicubu zesimiso se-endocrine-i-pituitary (njengenxalenye ye-hypothalamic-pituitary system), thymus, thyroid, i-pancreas, i-adrenals kunye ne-gonads). Kwakhona, imbangela yokwanda kwenani lama hormone wesilisa - kunye ne-androgens-isifo se-adrenogenital syndrome. Inani elikhulu lamahomoni wesilisa liguqulwa libe yi-glucocorticoids phantsi kwezenzo ze-enzyme ekhethekileyo, umveliso owenzekayo owenzelwe i-genetically. Esinye isizathu sokuba i-hyperandrogenism kubasetyhini kuthiwa yi-tumrenal tumors. Ukwanda kweseli ezivelisa i-androgens kwandisa kakhulu inani lamahomoni esilisa. Ukwandisa imveliso yamadoda e-hormone yesini nayo ingabangela ubundlubongela kwesikhumba kwi-sex hormone - testosterone.
I-Hyperandrogenia kwabasetyhini - iimpawu
I-Hyperandrogenia yimeko ebonakaliswa klinikhi ngamacne, seborrhea, kunye ne-hirsutismome kunye ne-androgen exhomekeke kwi-alopecia. Kule meko, iimvavanyo zegazi zingabonisa ukuphakanyiswa okanye kwindawo eqhelekileyo ye-androgens (i-hormone yesini). Utshintsho lwe-Ovari, uphawu lwee-ocys polycystic, luyafumaneka kwakhona. Into ebalulekileyo, nayo impawu yesifo se-hyperandrogenism kwabasetyhini, ebangelwa ukwanda kwe-androgens, kukuphulwa komjikelezo wokuya esikhathini, emva kokungabikho kwengqondo, ukujikeleza kwesantya. I-Hyperandrogenia kumantombazana ilibazise ukuqala kwesimo seminyaka emininzi.
I-Hyperandrogenism yabasetyhini ihamba kunye nokunyanya. Utshintsho kwesikhumba luhambelana nokubunjwa kwe-acne (blackheads). Kwakhona, i-hyperandrogenia ibangela utshintsho olungenakuguquka olukhokelela ekwakheni i-cysts encinci kunye nokwakhiwa kwe-capsule ejikeleze ii-ovari. Kwimiqondiso yangaphandle yamanqanaba aphakamileyo kunye nee-orrogens, ukukhuphuka kwe-acne, ukukhula ngokweqile kweenwele kwimilenze, izandla. Utshintsho olunzulu kwii-ovari lungavimbela ukuvuthwa kweqanda, i-polycystosis.
Hyperandrogenism nokukhulelwa
Iingcali zichonga i-hyperandrogenism ye-adrenal, i-ovarian kunye nemvelaphi edibeneyo. I-Hyperandrogenia ye-ovarian genesis ibangelwa ngumxholo okwandisiweyo wesifo se-hormone - testosterone, esenziwa ngama-ovari. Izimbangela zezi zifo zizifo ezahlukahlukeneyo zezi-ovari: izicubu, i-polycystosis. Kwakhona kuvame ukufunyaniswa kwiimantombazana ezisebenza kwimidlalo yamandla. Ngexesha lokukhulelwa, i-hyperandrogenia ye-ovarian genesis ayisongelo kumntwana kunye nokunikezelwa, kwaye ayifuni unyango. I-Adrenal hyperandrogenism, ngokuqhelekileyo i-congenital okanye ebangelwa ukungabikho kwenani leenzyme ezithatha inxaxheba ekwakheni i-cortisol, iyingozi kulabo abaceba ukukhulelwa okanye abakhulelwe.
I-Hyperandrogenia kwabasetyhini ngexesha lokukhulelwa kunokukhokelela kwiinkathazo eziyingozi sele zisondele ekuzaleni, njengokungaphumelelanga kwe-amniotic fluid kunye nokusebenza kwabuthathaka.