I-hormone evuselela iifolm (i-FSH) i-hormone eveliswa yi-hypothalamic-pituitary system, ngokuchanekileyo - kwi-pituitary. Ukulawulwa komveliso walo kwenziwa nge-hypothalamus, kwaye ukuxinwa kwe-FSH ngokuzithe ngqo kuxhomekeke kumgangatho we-hormone yesini egazini.
Ngokunciphisa okuncinci ukugxininiswa kwabo, ukukhuthazwa kwe-FSH iqulunqa kwenzeka, kwaye kwinqanaba eliphakamileyo - ukuhlanganiswa kwe-hormone yokuvuselela i-follic iyancipha. Kwakhona kunciphisa ukuhlanganiswa kwe-FSH i-inhibin-B, ekhoyo kwiiseli zamanqanda kunye nakwiimithi zamadoda ezincinane.
Imveliso yemveliso yehomoni
Ukuhlanganiswa kwe-FSH akuyiyo yonke into, kodwa isalathisi sokutsala. Ngaloo ndlela, xa i-hormone yokuvuselela i-follicle eyenza i-hormone ivuseleleke ibe yigazi legazi, ingxinano yayo iphakama ngokukhawuleza kwaye idlula imfuneko yesi-2, kwaye iphindwe kabili. Emva koko izinga liyehla. Uxinaniso oluphezulu luyabonwa kwinqanaba lokulandelelana lokuhamba kwimihla.
Amazinga e-FSH kumaxesha ahlukeneyo wobomi bowesifazane
Umxholo we-horlicone evuselela i-hormone egazini kwanoma yiyiphi na ibhinqa ayinayo ingqiqo kwaye iqheleke kwimida ye-1.7-135 IU / l.
Ngoko umxholo wale hormone kwigazi labesetyhini kuxhomekeke kwisigaba esithile (isigaba) somjikelezo wesini. Kwinqanaba lesilandelayo , i-FSH ivame ukuba ngu-3.49-13 IU / L, ekunciphiseni i-1.69-7.7. Ininzi enkulu ye-hormone ifinyelela ngexesha le-ovulation - 4.69-22 IU / l. Ngethuba lokukhulelwa kwangoku, ukuxinwa kwe-FSH kunciphisa ngokukhawuleza, kwaye kufinyelela kwi-concentration ye-0.01-0.3 IU / L.
Ngethuba lexesha le-postmenopausal, umxholo we-FSH ukhuphuka, okubangelwa ukuvimbela ukuhlanganiswa kwe-estradiol kunye neprogesterone. Ngeli xesha, ukuxinwa kwe-FSH kufinyelela ku-26-135 IU / l.
Umxholo we-hormone ovuselela i-hormone ungaphantsi kwesiqhelo, ekhokelela ekuphuhliseni:
- i-Callman syndrome;
- Ukungabikho kwemveliso yehommoni yi-pituitary gland;
- izicubu zamathambo amaqanda, amathambo.
Ngako oko, ukwandisa i-horlicone-stimulating hormone ngaphezu kwesiqhelo, kunokukhokelela kwizifo ezinjengoku:
- izifo zegonads;
- i-tumor;
- i-cyst ovarian;
- ukuphuhliswa kwamagonads;
- ubusuku bokuqala.
Nentsingiselo
I-FSH, ihlanganiswe kumzimba wesetyhini, ikhuthaza ukukhula komzimba kunye nokuqinisekisa ukulungiselela kwabo inkqubo ye-ovulation. Le hormone ilawula ngokuthe ngqo isigaba sokuqala somjikelezo wonke wokuya esikhathini, umjikelezo wesigxina. Ngaphantsi kwempembelelo yalo, ulandelelwano lukhula kakhulu ngobukhulu kwaye luqala ukuvelisa i- estradiol . Ekupheleni kwesigaba sobuqili, ukuxinwa kwe-FSH kwanda ngokukhawuleza. Emva koko i-follicle iyaqhaqhaza, kwaye ukusuka kuyo iqanda elivuthiweyo liphuma kwintsika ye-peritoneal, oko kukuthi, inqubo yokwenza i-ovulation yenzeke.
Ngexesha lesi-2 sesigaba somjikelezo, i-Luteal, i-FSH ikhuthaza ukuhlanganiswa ngqo kweprogesterone. Xa ibhinqa lifikelela kwiminyaka engama-45 ukuya kuma-50 ubudala, ukuphuma kwesisu, apho i-estradiol kunye ne-progesterone ayisaphinda iveliswe ngama-ovari, okukhokelela ekunyuseni kwinkxalabo emzimbeni we-FSH.
I-FSH iqulethwe kumadoda, kodwa kwixinzelelo elingaphantsi. Le hormone iqala inkqubo ye-spermatogenesis kubafana abaselula. I-FSH egalela ukuphuhliswa okuqhelekileyo kwee-tubini ze-seminiferous ze-male kunye nokwandisa izinga le-hormone testosterone.
Uxinzelelo oluphezulu lwe-FSH lubonakala xa abantwana bezalwa. Ngamakhwenkwe kunciphisa isiqingatha sonyaka, kwaye kumantombazana - kufinyelela kumgangatho okanye kwizinga leminyaka eyi-1-1,5. Ngexesha elizayo umxholo walo unyuke kuphela xa ufinyelela kwiminyaka yokuguquka, xa i-FSH ilawula inkqubo yokukhulelwa.