I-Hemoglobin iyiprotheni eyinkimbinkimbi. Emzimbeni womntu, unembopheleleko yokutshintshwa kwe-oksijeni kumathambo kunye nezitho. Ngamanye amaxesha le nto ingadibaniswa ne-glucose. Le nkqubo ibizwa ngokuba yi-glykirovaniem. I-hemoglobin eyenza i-glycosylated hemoglobin (i-HbA1C) - yinto ebonisa ukuba ngaba utshintsho olubalulekileyo luvela emzimbeni, kwaye ukuba kunjalo, bekude kangakanani bakwazi ukuhamba.
Uvavanyo lwegazi lubonisa ntoni i-hemoglobin ye-glycosylated?
Le ngcamango iquka kuphela loo nxalenye yeprotheni, eye isakwazi ukuthetha kunye nama-molecule ye-glucose. I-hemoglobin yeGlycosylated ilinganiswa ngeepesenti. Uhlalutyo lokumisela le nto luthembeke ngakumbi kunezinye iincwadi ezininzi ezibonisa inani leswekile egazini . Ngaphezu koko, idatha efunyenweyo ifake ixesha elaneleyo elide.
I-A1C - enye yamagama ahlukile e-compound - ngamanani amancinci angafumaneka kumzimba naluphi na, nokuba ngumntu onempilo. Uvavanyo oluqhelekileyo lwegazi lwe-hemoglobin ye-glycosylated ingabonwa ukuba inani leprotheni alidluli 5.7%. Kwizigulane ezinesifo sikashukela, esi sibonakaliso sisoloko sinyuka ngamibini okanye emithathu, okanye ngaphezulu. Ukuba i-HbA1C emzimbeni ayanele, izifo ezinjenge-hemolytic anemia okanye i-hypoglycemia inokukrokra. Isixa sempahla siyancipha ngokukhawuleza emva kokumpontshelwa igazi okanye imisebenzi enzulu.
Ngokukhawuleza ndifuna uku lumkisa: ukukhathazeka kwangaphambi kwexesha akuyimfuneko. I nyaniso yokuba i-glycosylated hemoglobin yanda ayithethi ukuphuhliswa kwesifo sikashukela . Isalathiso esingaphezulu kwe-6.5% kuthathwa njengengozi. Kule meko, ukuxilongwa "kwesifo sikashukela" kusenziwa ngokuqinisekileyo ngokuqinisekileyo, nangona uvavanyo olongezelelweyo lunokuyichasa.
Ukuba izinga le-A1C libubanzi ukusuka kuma-5.7 ukuya kuma-6.5 ekhulwini, ke kukho umngcipheko wokuphuhlisa eso sifo. Ukuthintela isifo sikashukela, kufuneka uphinde ucinge ngokukhawuleza indlela yakho yobomi, ukuba kunokwenzeka, ungene kwimidlalo, ngaphandle kokutya okunamafutha, ukutya okutyiweyo kunye nezondlo ezingenampilo. Ukuba isigulane sinamathela kuyo yonke imimiselo, inani leprotheni liya kubuya kwinqanaba ngenyanga.
Idatha, ebonisa ukufundwa kwe-hemoglobin ye-glycosylated egazini, yenza ukuba kubekho iingcali ezingagcini nje ukuxilonga, kodwa kwakhona ukuphonononga ukuphumelela kwonyango kwaye, ukuba kuyimfuneko, ukuyilungisa. Ngendlela, ungathatha uhlalutyo kubantu abadala kunye nabantwana. Iimimiselo zezinto zifana nezigulane ezahlukeneyo.
Ndingayifumana njani i-blood test ye-hemoglobin ye-glycosylated?
Iingcali zincoma ukuthatha igazi kwi-hemoglobin ye-glycosylated njalo emva kweenyanga ezintathu. Oku kuya kwenza kube lula ukugcina izinga le-HbA1C phantsi kolawulo kwaye, ukuba kuyimfuneko, uthathe amanyathelo afanelekileyo. Abantu abangabikho kwisifo sikashukela kufuneka benziwe ubuncinane kanye emva kweenyanga ezintandathu.
Ezinye iibhoratori zichaza ukuba i-hemoglobin ye-glycosylated i-hemoglobin ayixhomekeke ekubeni igazi lilinikiweyo okanye cha. Kodwa ukuba uthembele kwiziphumo zolu phando, kusengcono ukuya kwidingo lovavanyo ekuseni.
Ukugxotha ukutyelela kwibhubhoratri kufuneka kwakhona kunikwe izigulane ezasinda kwigazi okanye ukuphuma kwegazi. Ngenxa yale miba, izixhobo zokuhlalutya zinokuphazamiseka kakhulu.
Nangona inkcazo ye-glycosylated hemoglobin yinkqubo kwaye iyabiza, inamathuba amaninzi:
- Uhlalutyo alukwazi ukuphazamisa ukushisa kunye nezifo.
- Isimo sengqondo sesigulane asichaphazeli umphumo wesifundo.
- Icandelo le-A1C limiselwa ngokukhawuleza.