Ngaba wakha wacinga malunga nokuba kutheni izidakamizwa ezinomxholo ofanayo zihlala zineendleko ezahlukeneyo? I-ididium eyaziwayo iyabiza kakhulu kuneLoperamide, kwaye emva koko zonke iziyobisi zifana ngokufanayo, zinomzimba osebenzayo. Iimpawu zokusetyenziswa kweLoperamide ziya kufana, kwaye ixabiso layo liya kukumangalisa. Ziyintoni ukubanjwa?
Izixhobo zeLoperamide Hydrolochromide
Ngokwakheko lwe-Imodium kunye neLoperamide, enye yecandelo liLoperamide hydrochloride, izibonakaliso zokusetyenziswa zilandelayo:
- isifo sohudo ;
- isifo sohudo;
- ukuqheleka kwamathumbu emathumbu emva kokuhlinzwa.
Ezi zibonakaliso zeLoperamide zibangelwa kukuba i-substance inesiphumo esisichukumisayo kwimisipha ehamba kakuhle emathunjini kwaye ngenxa yoko ukugcinwa kwesitophi kwenzeka. I-Loperamide ibhekisela kumalungiselelo opioid kwaye ivela kwi-piperidine. Ikhusela isenzo sabamkeli bamathumbu abanobuchule kwi-opiates kwaye ngaloo ndlela kubangela ukuba i-sphincter ivumelwano, kunye nemisebenzi yemoto ukuba ifakelwe. Ekuqaleni, isilwanyana esasetyenziselwa ukuphatha igastroenteritis kunye neentlobo ezahlukeneyo zokuvuvukala kwamathumbu, namhlanje zisetyenziswa ngokuyinhloko ukulwa nesifo sohudo.
I-Loperamide yafunyanwa yizinzululwazi zaseBelgium ngowe-1969 kwaye ukususela ngoko kuye kwakhuthazwa ngokunyanisekileyo kwimarike phantsi kwegama elithi Imodium. Ngokufanayo, kumazwe amaninzi, izifaniso zesilwanyana ezinomxholo ofanayo zikhutshwe. Ekhaya laseLoperamida-Akri ngokupheleleyo impawu ezifanayo kwisicelo. Kodwa ke ezinye zeziyobisi zihlukile, oko kukuthi-isilinganisi sokuhlanjululwa kwezinto ezisetyenziswayo, izinga lokulawula kwimveliso kunye nokufumaneka kwezifundo ezintsha kwimveliso. Oku kunengqiqo, kuba imveliso engaphezulu, imali engabelana ngayo loo mibuzo.
Ngokomzekelo, ngo-1990, uJohnson noJohnson, owayengokukhuthaza i-Imodium, washiya eso sirhweba kwiimarike ngenxa yokufa kwamanye amazwe ePakistan. Emva kokusetyenziswa kwe-Imodium, abantwana abangama-19 babandezeleka. Uphononongo oluqinileyo lwe-loperamide kule nto aluzange luphele kwaye le mpendulo yahlaziywa. Inyani kukuba kubantwana kwaye, ingakumbi, iintsana, i-piperidine kunye neziphumo zayo zikhokelela ekugxineni kwemisipha yamathumbu kuze kufike ukukhubazeka. Njengomthetho, umphumo onjalo ubonakala kubantwana abaneminyaka engaphantsi kweminyaka emi-2 ubudala, ekudala ubudala ukuphulwa okunjalo akunzeki. Nangona kunjalo, ukusetyenziswa kweziyobisi, kuquka i-loperamide, kumazwe amaninzi kuvunyelwe kuphela kubantwana abangaphezu kweminyaka engama-6 ubudala, nase-Australia, abantwana abangaphezu kweminyaka engama-12 ubudala.
Isisombululo kunye nokulawulwa kweLoperamide
Ukuze unyango lwe-diarrhea enamandla, abantu abadala banikwa umthamo wokuqala weLoperamide kwisixa semali engama-4 mg, ehambelana nama-capsules a-2 eziyobisi. Kwixesha elizayo, thabatha u-2 mg wamachiza emva kwesibini, ukuba iyaqhubeka ibe mnene, i-liquid. Kwimeko apho isitulo siqhelekileyo, okanye isigulane sinokuqhawulwa , ukusetyenziswa kwamacwecwe aseLoperamide kufuneka kupheliswe.
Ukunyanga kwesifo sohudo esingapheliyo, abantu abadala baqeshwe ngo-2 mg yesilwanyana rhoqo ngamaxesha ama-2 de iimeko zizinzileyo.
Abantwana abangaphezu kweminyaka engama-6 ubudala bakhethwe ngabanye kwaye basekelwe ubunzima bomzimba womntwana. Unyango
Umthamo omkhulu wemihla ngemihla yeLoperamide kubantu abadala i-16 mg, kubantwana aba-6-8 mg.
Xa unyango lwe-soya ye-diarrhea "," i-diarrhea "ye-allergic ne-nerrhea, i-drug isilawulwa ngokwecwangciso efana nokunyangwa kwesifo sohudo.
Ngokunyamekela, uLoperamide ilawulwa ngenxa yokuphulwa kwesibindi kunye neentso. Isilwayo siyaphikisana:
- khulelwe;
- oongikazi;
- abantwana ukuya kwiminyaka eyi-6.