Kutheni umzimba udinga i-GSBG?
Emzimbeni womntu, i-testosterone ijikeleza, ngokukodwa kwifom eboshiweyo, ngokubambisana ne-GHPS, ngokuthe rhoqo, nge-albumin. Ukuhluka okufanayo kwi-SHBG kuphazamisa ukuxinwa kwe testosterone egazini.
Inqanaba lokubambisana, ngokuthe ngqo kwi-SHGG, kuxhomekeke ekuxininiseni kwe-hormone yesondo. Ngoko, ukwandisa izinga le-estrogen kwandisa ukuhlanganiswa kwayo. Ngako oko, umxholo wale hormone egazini labesetyhini uphakamise kabini kunaloo madoda. Kanye kunye nokwehla kwimveliso ye-estradiol, umxholo we-SHBG kwigazi labasetyhini uyancipha.
Inqaku le-SHBG linqunywe njani kwabasetyhini?
Ngamanye amaxesha abasetyhini abanikezelwa ukuhlalutya i-SHGG bayazi ukuba yintoni, kunye nendlela yokuchaza ngayo iziphumo zayo - abanalo ingcamango. Okokuqala, kuyimfuneko ukwazi ukuba yiyiphi inqanaba le-SHBG kufuneka liqheleke kubafazi. Kufuneka ukuba kuqaphele ngokukhawuleza ukuba ukugxininiswa kwigazi akuzinzile, kwaye kuxhomekeka kwizinto ezininzi. Ukunyuka okanye ukunciphisa kwayo kungaqatshelwa kwiimeko zokugula.
Utshintsho kwinqanaba le hormone lugcinwa njengoko iminyaka ikhula. Ngaloo ndlela, kwabasetyhini:
- 8-10 iminyaka - 26-128 i-nmol / l;
- 10-12 - 16-112 i-nmol / l;
- 12-14 iminyaka - 19-89 i-nmol / l;
- 14-60 iminyaka-18-114 i-nmol / l.
Kananjalo ukuxilongwa kwezifo kusetyenziswa rhoqo, okubizwa ngokuba yi-IST (i-testosterone index). Ichazwe kwisiqingatha se testosterone emzimbeni womntu kwi-SHGG. Ngaloo ndlela, kwabasetyhini le ngcaciso iyahluka phakathi kwe-0.8-11%, kumadoda yi-14.8-95%.
Kutheni inqanaba le-SHBG kwigazi labasetyhini lonyuswa?
Ngokuqhelekileyo kukho iimeko apho izinga le-SHBG kwabasetyhini egazini landa. Okokuqala, kungabangelwa ngu:
- ukwanda kwimiqathango ye-estrogens egazini lomfazi;
- imeko ye-hyperthyroid - ibonwe kwi-pathology ye-thyroid gland;
- i hepatitis;
- Usulelo lweHIV;
- ukufumana i-hormonal contraceptives, eninzi iqukethe i-estrogens.
Ngenxa yintoni ukuhla kwezinga le-SHBG egazini?
Kuloo matyala xa i-SHBG yabasetyhini iyancipha, bathetha ngokuphuhliswa kwezilwanyana. Kwiimeko ezininzi zezi:
- i-nephrotic syndrome (ukuphazamiseka kwenkqubo ye-excretory);
- ukwandiswa kwamanqanaba e-androgens egazini- hyperadromia ;
- isifo sikashukela ;
- i-acromegaly;
- Isifo sikaCushing;
- ukwanda kwamanqanaba eprolactin egazini;
- I-polycystic ovarian syndrome;
- i-cirrhosis yesibindi;
- imithi, ngokukodwa: iDanazol, iSomatostatin, kwakunye nemichiza ene-androgens kunye ne-glucocorticoids.
Indlela yokulawula izinga le-SHBG?
Ukuze kuqinisekiswe izinga le-SHBG emzimbeni wowesifazane, isampuli yegazi isenziwa. Imiqathango elandelayo kufuneka ibonelelwe:
Uhlalutyo lwenziwe kwisisu esingenalutho, kusasa. - Iiyure ezingama-72 phambi kwenkqubo, kuyimfuneko ukukhansela ukungenisa zonke iziyobisi ze-hormonal.
- Musa ukulala ngesondo.
Ngokuqhelekileyo isiphumo sokuhlalutya sele sisaziwa emva komhla. Ngelo xesha, ukulungiswa kwayo kufuneka kwenziwe kuphela ngugqirha. Ngaloo ndlela, ukuba uyazi ukuba lo ngu-SHGG, kwaye oko kuyenziwa, umfazi akufanele akhathazeke emva kokufumana isiphumo sokuhlalutya, kwaye akukho mfuneko ukuba enze izigqibo ezizimeleyo, kodwa ngokuqinisekileyo uya kufuna iingcebiso kwi-gynecologist.