Kungekudala, ingqalelo ehlawulwe kwi-immunological yindoda engabikho. Emva kokuqhuba uphando oluninzi kwacaca ukuba isizathu salezi zi-antibodies ze-antisperm, ezakhiwa ngamadoda kumathambo kunye nezixhobo zazo. Kodwa esinye isiphumo se-spermogram akwanele ukutyhila ngokupheleleyo imbangela yokungasebenzi. Ngako oko, ukwenzela ukuba wenze uvavanyo oluchanekileyo, oogqirha banikeza isincomo sokuhlalutya kwesinye sezilwanyana - uvavanyo lwama-MAR ("umxube wokuxutywa kwamanzi", okoqobo oku kuthetha "ukuxutywa kwamanzi").
I-Antigens kule meko yimbumba kwi-spermatozoa. Ukuba abanakukwazi ukujamelana ne-antisperm antibodies, ke i-spermatozoon ihlanganiswe nebhubhane le-antispermic elivimbela ukunyakaza kwayo.
Ukuhlolwa kwe-MAR kwenza ukuba kube lula ukufumanisa ezi zikhusela okanye ziqinisekise ukungabikho kwazo.
I-spermogram evamile ayivumeli ukutyhila le pathology, kuba kuloluhlalutyo, i-spermatozoon, eyonakaliswe ngama-antibodies antisperm, ibonakala iqhelekileyo. Kodwa ngexesha elifanayo, akakwazi ukutshiza iqanda kwaye eqinisweni ayilunganga. Ukuhlolwa kwe-MAR kwenza ukuba kube lula ukucacisa umlinganiselo we-spermatozoa eyonakaliswe ngama-antibodies, kwisixa esipheleleyo esakhutshwa kwi-ejaculate enye. Kwaye uyakwazi kuphela ukubonisa inani elichanekileyo le-spermatozoa enempilo ekwazi ukuthatha inxaxheba kwinkqubo yokuchumisa. Ukuba iziphumo zovavanyo lwe-MAR zinyanzele, oko kuthetha ukuba inani elivumelekileyo leengqungquthela, ke ezinye izizathu zokungabikho kwindoda zifunwa.
Iimbangela zokubonakala kwe-antisperm antibodies kumzimba wesilisa
Enyanisweni, izizathu zokubangela ukuba umzimba womntu uqale ukulwa namaseli akhe aphilileyo:
- ukwamkelwa kweerumas ezitho zangasese (kubandakanywa ukungenelelo kokungenelela);
- ukuphulwa komqobo phakathi kwemithambo yegazi kunye nemigodi yamanzi;
- ubukho bentsholongwane;
- isifo se-urrogenital;
- kukho izizathu zokuvela ngokungaqhelekanga;
- ukulala ngokwesondo (ubuninzi beeprotheni zangaphandle kubonwa ngumzimba njengengozi).
Izibonakaliso ngenjongo yovavanyo lwe-MAR
Uvavanyo lokumisela ubukho okanye ukungabikho kwe-anti-antibodies ye-antisperm kumiselweyo xa kutholakala kwi-spermogram ye-pathologies ye-spermatozoa njenge:
- uhlutha;
- ulwahlulo;
- ukuhamba kwehla;
- Ukungafiki ixesha elide lokukhulelwa kwisibini esitshatileyo;
- ukulungiselela i- IVF ne- ICSI .
Ukuba ugqirha unyule olu hlalutyo, kuya kuba ngcono ukuthatha uvavanyo lwama-MAR kwi-laboratory yezobugcisa obuphezulu, ngokuba izixhobo eziphambili kakhulu zisetyenziselwa ukucwangciswa kwezinto eziza kuhlalutya, ezichaphazela ngokuchanekileyo ukuchaneka kohlalutyo oluchanekileyo.
Uvavanyo lwama-MAR for antibodies antibodies lubonisa ukufumana kwabo kungekuphela kokubhalwa kwesidoda, kodwa kunye nokuhlalutya kwe-serum. Ukumiswa kwemvavanyo ye-MAR:
- Uvavanyo lwe-MAR-oluqhelekileyo - xa iziphumo zohlalutyo zingabonakali i-spermatozoa eyonakaliswe ngama-antibodies antisperm.
- Uvavanyo lwe-MAR-negative lithetha ukuba inani le-spermatozoa elonakalisiweyo alikho ngaphezulu kwe-50%. Esi sibonakaliso sinokucingwa njengesiqhelo.
- Uvavanyo lwe-MAR lukhangelekile, luqwalaselwa xa uhlalutyo lubonisa ukuba inani le-spermatozoa kwi-shell ye-antispermic ingaphezu kwe-50%. Esi sibonakaliso sibonisa ukuba kunokwenzeka ukuba umntu ongenalo ukukhulelwa kwe-immunological.
Ukuba uvavanyo lwe-MAR lubonise umphumo omuhle we-100%, ngoko ke ukuchumisa ngokwemvelo kwindoda ehlolisweyo akunakwenzeka. Kule meko, oogqirha bacebisa ukusebenzisa indlela yokukhulelwa nge-IVF ne-ICSI.