Iprogesterone yi-hormone ye-steroid eveliswa ngumzimba wesetyhini kunye nendoda, ngokukodwa amathambo kunye nama-ovari athatha inxaxheba ngokungafunekiyo kwi-correnx ye-adrenal. Iprogesterone ithathwa njenge-hormone yokukhulelwa: iveliswa ngumzimba ophuzi ukuya kwiintsuku ezili-12 ukuya kwe-14 ngaphambi kokuqala kokuya esikhathini, kwaye ekuqaleni kokukhulelwa kwayo inqanaba lihlala liphakanyisiwe kude kube liviki le-16 lokukhulelwa, xa umsebenzi we-hormone yokuvelisa kunye nokutya okunomsoco kuqhutyelwa yi-placenta.
Xa uvavanyo lwe progesterone?
Ixesha elifanelekileyo kakhulu lokuthatha iimvavanyo kwinqanaba leprogesterone kubasetyhini abakhulelweyo lixesha ukuya kwiinyanga ezi-4 zokukhulelwa. Ngokuqhelekileyo uhlalutyo lunikezelwa ngexesha lokubhalisa, kwaye ngokukhawuleza emva kwayo.
Kubafazi ngaphandle kombuzo, xa banikela ngegazi kwi-progesterone, kufuneka bavunyelwane noogqirha. Emva kwakho konke, ngomjikelezo weentsuku ezingama-28, igazi leprogesterone kufuneka linikezelwe ngomhla we-22 womjikelo, oko kukuthi, emva kokuvuthwa, xa izinga lalo likhulu. Ngomjikelezo omde, umzekelo, ukuya kwiintsuku ezingama-35, i-progesterone ihanjiswa ngomhla we-25-29 womjikelo. Ukuhanjiswa kwe-hormone nayiphi na imeko kufuneka iwele kwisigaba sesibini somjikelezo.
Indlela yokuthatha iprogesterone ngokuchanekileyo?
Nakuphi na uhlalutyo, ngaphandle kweemeko zesikhashana, kunemiqathango ethile yokuhanjiswa. Uhlalutyo lweprogesterone lwenziwe kwisisu esingenanto, emva kokutya kokugqibela kufuneka kudlule iiyure ezingama-6 ukuya kwe-8. Kucetyiswa ukuba uthathe uhlalutyo kusasa, kodwa ukuba ugcina ixesha eliphakathi kweeyure ezingama-6 phakathi kokutya, lingafumaneka emva kokutya.
Ixesha lokuthatha i-progesterone ye-17-OH?
17- I-progesterone ayiyona hormone, kodwa iyandulela ngaphambili, ngoko ithathwa iintsuku ezine-5 zomjikelezo. Ngexesha lokukhulelwa, ukuhlaziywa kwe-progesterone ye-17-OH ayikho inkcazelo kakhulu, njengoko kubaluleke kakhulu imvelaphi yayo ngaphambi kokukhulelwa kunye nosana oluzalwayo.
IiRhafu zeprogesterone
Ukuxilongwa kwama-hormone ngokuthe ngqo kuxhomekeke kwisigaba somjikelezo, ukugxininiswa okuphezulu kwisigaba esilandelayo.
Progesterone:
- Isigaba sokulandelelana - 0,32 - 2,23 i-nmol / l;
- isigaba se-ovulatory - 0.48 - 9.41 i-nmol / l;
- isigaba sokufunda - 6.99 - 56.63 i-nmol / l.
Xa ukhulelwe, amanqanaba e-progesterone anjengale ndlela:
- I-trimester - 8,9 - 468,4 i-nmol / l;
- II trimester - 71.5 - 303.1 i-nmol / l;
- III trimester - 88.7 - 771.5 i-nmol / l.
Isilinganiso seprogesterone kumadoda ngu-0.32-0.64 i-nmol / l.
Uhlalutyo lwe-progesterone kufuneka lunikezelwe ukulungiselela ukukhulelwa, kunye neengxaki ze-adrenocortical (isifo sika-Addison), kwaye kukho iimeko ezinxulumene nokwanda kwinqanaba leprogesterone:
- khulelwa;
- ukuhluleka kwezintso;
- i-humorrhea;
- i-cysts yomzimba ophuzi ;
- izilonda zepentecenta;
- kuphuma igazi.
- Inqanaba eliphantsi leprogesterone libonakaliswe ngolu hlobo:
- ukukhulelwa kwangaphambili;
- usongelo lokukhulelwa kwesisu;
- ukuphuma kwegazi;
- ukuvuvuka okungapheliyo kwendawo yesini;
- ukulibaziseka ekuphuhlisweni komntwana;
- ukuthatha amayeza athile.
Xa uthatha nayiphina imithi ngelixa uthabatha uvavanyo lweprogesterone
Inqanaba elongeziweyo leprogesterone kubasetyhini linakho ukubonisa ukukhulelwa, ngelixa emadodeni kuwuphawu lweenkqubo ezingenayo i-adrenal glands okanye i-testicles.
Ukulungiswa kokuphulwa kwezinga leprogesterone ngokuqhelekileyo kusetyenziswe iinjongwane zeprogesterone 1%, 2% okanye 2.5% - izixazululo ze-hormone ezinamafutha, ngokuqhelekileyo kwi-almond okanye kwioli yeoli, okanye iifom ye-progesterone, evumela ixesha elifutshane ukuba lilungele imvelaphi ye-hormonal.