Esinye sezibonakaliso ezibalulekileyo, esinqunywe ngokuhlalutya kwegazi, lizinga le-monocytes egazini. I-Monocyte zihlobo lwe-leukocyte. Lawa awona maseli amakhulu kwaye asebenzayo aphuma kumnayile obomvu. Kanye kunye nokuhamba kwegazi, i-monocytes ekhulile ingena izicubu zomzimba kwaye ihlaselwe kwi-macrophages. Umsebenzi oyintloko wale nxalenye yegazi kukutshatyalaliswa kunye nokuxutywa kwee-microorganisms ezifakwe emzimbeni, kunye nokupheliswa kwezinto eziseleyo. Ngokumalunga nelokuba i-monocytes yenza umsebenzi onoxanduva, kuthiwa "i-janitors yomzimba." Ziyi-monocytes eziba ngumqobo ekuvelweni kwamaseli e-thrombi kunye nomhlaza. Ukongezelela, i-monocytes ibandakanyeka kwinkqubo ye-hematopoiesis.
Isiqhelo se-monocytes egazini
Ukuze ukwazi ukuba ingaba ixabiso legazi elifunyenwe kuhlalutyo (kubandakanywa nenqanaba le-monocytes) lihambelana nomgangatho, kuyimfuneko ukuba ube nombono wesiqhelo se-monocytes kwiindwendwe ezipheleleyo.
Isiqhelo se-monocytes egazini sisuka ku-3% ukuya kwi-11% yenani leytocytes okanye malunga neeseli ezingama-400 nganye kwi-1 ml yegazi le-peripheral (oko kukuthi, igazi lijikeleza ngaphandle kweempawu ze-hematopoietic). Isiqhelo se-monocytes egazini labasetyhini sinokuba ngaphantsi komda osezantsi kwaye i-akhawunti ye-1% yenani lecycytes.
Kwakhona inqanaba lamaseli amhlophe lihluka ngobudala:
- Umxholo we-monocyte egazini lentsha elusandul 'ukuzalwa usuka kwi-3% ukuya kwi-12%;
- xa iiveki ezimbini zifikeleleke, inqanaba lifikelela kwi-15%;
- umntwana oneminyaka eli-1 ubudala uthathwa njenge-4-10%.
Xa usukhulile, inani eliqhelekileyo le-monocytes egazini lidlula li-8%.
Tshintsha kwinqanaba le-monocytes egazini
Ukwandisa kwi-monocytes
Ukwandisa izinga le-monocytes kumntwana, nangama-10%, iingcali zihlala zizolile, ekubeni utshintsho olunjalo luhamba kunye neenkqubo zendalo ezihambelana nobuntwaneni, umzekelo, ukutshintsha. Ukugqithisa inani elifanayo le-monocytes xa kuthelekiswa nokuqhelekileyo kunye nokuhlolwa kwegazi jikelele kumntu omdala kubonisa ukungaphumeleli ekusebenzeni kwenkqubo yokujikeleza, kwakunye nokuphuhliswa kwesifo esithathelwanayo, njengokuba:
- isifo sofuba;
- i-syphilis;
- enteritis;
- brucellosis ;
- lupus erythematosus;
- i-rheumatoid arthritis;
- i-mycosis, njl
Ukuchithwa kwimixholo ye-monocyte kunokubonisa ukuphuhliswa kwesakhiwo esibi emzimbeni. Ngokuqhelekileyo ukwanda kwenani lamaseli amhlophe kuboniswa kwithuba lokugqibela emva kokusebenza. Kubasetyhini, isizathu solu tshintsho luhlala lusebenza ngokuthandana.
Ukunciphisa i-monocytes
Ukuncipha kwinqanaba le-monocytes yinto engabonakaliyo ngaphezu kokunyuka kwesi sixalathisi. Akuthethi kubonakalisa ukuphuhliswa kwesi sifo. Ngokomzekelo, abaninzi abafazi baye banciphisa i-monocytes ngexesha lokukhulelwa kunye nexesha lokuhamba emva. Kulo xesha nje ngenxa yokudinwa komzimba kunokubonakalisa i-anemia.
Ezinye izizathu eziqhelekileyo zokunciphisa umxholo we-monocyte egazini:
- Ezinye izifo ezithathelwanayo, kwindawo yokuqala, i- typhoid fever ;
- nkunkuma yelifa;
- kwamkela i-corticosteroids kunye ne-cytostatics;
- izifo ezinxulumene nomonakalo kwiiseli zengqondo.
Ukunciphisa umgangatho wee-monocytes udlalwa rhoqo kwixesha lokusebenza emva kokufakelwa komzimba. Kodwa kulo mzekelo kubangelwa ngokuzikhusela ngokukhusela umkhuhlane kunye neziyobisi ukwenzela ukuba uthintele umzimba ukuba ungayinqabeli iifomthi kunye namalungu.
Kwimeko nayiphi na into, utshintsho kwimixholo ye-monocyte egazini yeso sizathu sokufumana uviwo lwezonyango ukwenzela ukuchonga imbangela kwaye, ukuba kuyimfuneko, ukuqhuba unyango olufanelekileyo.