I-Cushing's syndrome isifo apho umzimba wenja iimeko zokuhlala uxinezelekile. Kwizilwanyana eziphilileyo, xa imeko iphikisayo, izilonda ze-adrenal, ngomyalelo we-pituitary gland, zifake i-hormone i-cortisol ye-steroid. Le hormone iququzelela umzimba wezilwanyana, unceda ukusinda kwimiphumo engebiyo ngaphandle kwelahleko. Kwaye kwizinja eziphethwe yisifo sikaCushing, izigulane ze-adrenal zikhulula ngokukhululeka inani le-cortisol.
I-Cushing's Syndrome - Iingxaki
I-Cushing's syndrome yinto eqhelekileyo yesifo se-endocrine yezinja. Kwiimeko ezininzi, zixhamla kwizilwanyana zamandulo kunye nobudala obuphakathi. Isifo sikaCushing siyinja yazo zonke iintlobo, kodwa iindawo ezibonakalayo ezibonakalayo zibonakaliswe kwiifolda ezincinci , i-terriers, i-dachshunds kunye neebhokisi . Kwaye izizathu zezifo zi:
- isifo sesinye okanye zombini i-adrenals, evuselela ukugcinwa okungalawulwayo kwe-hormone;
- i-adenoma ye-pituitary gland, i-orgring organ ekhupha i-horrenone ye-adrenocorticotropic.
Kulula kakhulu ukukrokrela isilwanyana sakho sesifo. I-Cushing's syndrome kwizinja iye yabonisa iimpawu:
- ukoma okweqile kwaye ukuvuthwa ngokuqhelekileyo yimiqondiso eqhelekileyo yesifo;
- Ukubonakala okungekho mzimba kwengubo kunye nokubonakala kweendawo ezinkulu ezilinganiselweyo ze-bald kwi-trunk, umsila nentamo;
- Ukupheliswa kwe-esrus kwiintsimbi;
- ukuhamba kweenja kuncitshiswa kakhulu;
- ukubunjwa kwezilwanyana kushintsho kakhulu: ngenxa ye-atrophy ye-muscle, isisu seso sikhulu kakhulu, ubukhulu bamathambo angaphantsi kancinci.
Ngenxa yoko, inja ibonakala iyincinci kunye nesisu esikhulu esingaqhelekanga kunye neendawo ezinkulu ezinqabileyo.
Unyango lwe-Cushing's syndrome kwizinja
Ukubhekiselele kwinkonzo yezilwanyana ngeempawu ezinjalo ngokukhawuleza kufuneka uqaphele ingcali kunye nokubangela ukusola malunga nobukho beCushing. Kodwa ngaphambi kokuqala unyango, ugqirha kufuneka enze uvavanyo oluchanekileyo kwaye achaze iqumrhu elichaphazelekayo. Xa ukufumanisa i-tumor kwi-adrenal glands, zisuswe kwaye zenze i-hormone yonyango.
Iimeko kunye ne-adenoma ye-pituitary gland yinkimbinkimbi kakhulu. Ngolu hlobo lwesifo, isilwanyana simiselwe iziyobisi ezivimbela ukuveliswa kwe-cortisone. Kodwa amayeza asebenzayo akhutshwa kuphela e-USA, Canada okanye eJamani, kwaye iindleko zabo ziphezulu kakhulu. Kwaye izindlu ezingabonakaliyo zasendlini zingasebenzi kwaye iziphumo zabo aziqondi kakuhle.