Izizathu zokunyuka kweprolactin kubasetyhini ziinguqu zenyama kumzimba okanye kwiimeko zokugula.
Ukuphakama kwemvelo kweprolactin
Makhe sihlolisise ngakumbi ukuba kutheni i-prolactin yabasetyhini iphakama, kwaye yiziphi utshintsho ezinokuxhunyezwa. Ukwanda kwenyama yeprolactin kubonakala ngexesha lokulala. Ngeyure emva kokuvuswa, izinga le-hormone liye linciphisa amanqanaba aqhelekileyo. Ukunyuka okulinganayo kwinqanaba lehommoni kunokwenzeka emva kokutya okunomlinganiselo omkhulu weprotheni, kwakunye neemeko ezixinzelelekileyo. Kuyaziwa ukuba ukulala ngesondo kuyishukumisi esinamandla sokumisa kunye nokuqedwa kweprolactin. Kwizizathu zokunyuka komzimba kwinqanaba leprolactin kubasetyhini kubalulekile ukubandakanya ukukhulelwa kunye nexesha lokutya ngesifuba.
Ukwandiswa kwamanqanaba eprolactin njengempawu zesifo
Amanqanaba eprolactin aphakanyisiwe kwi-pathologically egazini ngokuqhelekileyo enza ukuba kubekho iimeko zokungena kwexesha lokuhlala kunye nokukhokelela ekungenakwenzeka kokuzala. Ngaloo xesha kukho ukukhulelwa kwexesha elincinci. Ukongezelela, ukwehla kwesifiso sesondo kuyimpawu.
Ngaphantsi kwexesha elide leempembelelo ze-hyperprolactinemia, i-cysts kwi-mammary gland kunye nokuphuhliswa kwezinto zokugcina izinto.
Njengoko ubona, iimpawu zeli meko azilona nengozi. Ngoko ke, ngaphambi kokuba uqale unyango, kubalulekile ukufumanisa ukuba kungani iprolactin iphakanyisiwe kwabasetyhini, kuba kubalulekile ukuqeda imbangela yale mqathango.
Ukususela kwiimeko zokugula, ezi zifo ziyakubangelwa imbangela yeprolactin ephezulu kwabasetyhini:
- Izidumbu ze-pituitary kunye ne-hypothalamus, ezihamba kunye nokunyuswa kweprolactin. Kunokwenzeka njengeplalacininoma ekhethiweyo, kunye ne-tumor evelisa inani elongezelelweyo lamahomoni amaninzi.
- Ukutshatyalaliswa kwe-hypothalamus yesifo sofuba, i-sarcoidosis, kunye ne-irradiation yelungu.
- Ukunciphisa ukwakheka kwamahomoni e-thyroid.
- I-polycystic ovary , xa kukho ukungasebenzi kakubi kwi-hormone yesondo.
- Izifo zesibindi, ukuhluleka kwesibindi esingapheliyo. Ubukho be-hyperprolactinemia kule meko kubangelwa ukuphulwa kwe-metabolism ye-hormone.
- Izifo ze-correnx ye-adrenal, ekhokelela ekukhuselweni kwe-androgens kwaye, ngenxa yoko, ukungalingani kweprolactin.
- Ukukhiqizwa kwe-Ectopic yehomoni. Ngokomzekelo, nge-carcinoma kwinkqubo ye-broncho-pulmonary, iiseli ze-atypical ziyakwazi ukuvelisa ama-hormone.
- Ukutywala kwezilwanyana ezithile ezifana neuroleptics, i-tranquilizers, i-anti-depressants, i-estrogen-progestogen kunye nabanye.
- Kwezinye iimeko, isifo sikashukela esikhatywayo kwabasetyhini sihamba kunye nokwanda kwinqanaba leprolactin.