I-Ampicillin yintsholongwane ye-antibiotics ye-antibiotic action of a number of penicillins. Isenzo senkunkuma esebenzayo yesichengiso sijoliswe kukutshatyalaliswa kwembrane yeeseli ezincinci, kunye nokunciphisa iinkqubo ze-metabolism, oko kukuthi, ukuhlanganiswa phakathi kweebhokhwe zamaseli ezintsholongwane, ezibavimbela ukuba zande kwaye zichithe iiseli ngokwazo. Impembelelo ye-Ampicillin inobungozi kwi-Gram-positive, i-Gram-negative bacteria, kunye nezifo zamathumbu emathumbu.
Isichengisi si-acid-fast. Le propati ayivumeli ijusi yesisu isichaphazele kakhulu iichiza xa itywayo, ukuxhwaba ku-40% kuphela. Ukuhlanganiswa akukwenzeka, isicatshulwa sidityaniswe ngaphandle kwe-biotransformation. U-Ampicillin uncedo kwiziganeko apho amanye amayeza angakwazi ukujamelana nokusuleleka.
Iimpawu zokusebenzisa i-Ampicillin
Ekubeni i-Ampicillin inomsebenzi obanzi, ukutshabalalisa iintlobo ezininzi zeebhaktheriya, isetyenziselwa ukuphatha ezininzi izifo kwiinkqubo ezahlukeneyo zomzimba.
1. Izifo zokuphefumula kunye ne-ENT amalungu ase-Ampicillin anqunywe unyango lwezi zifo:
- pharyngitis;
- tonsillitis;
- sinusitis;
- angina;
- mkhuhlane o lubomvu;
- laryngitis;
- bronchitis;
- ukungabikho kwemiphunga;
- pneumonia;
- bronchopneumonia;
- pleurisy;
- otitis media.
2. Ngezifo ze-genitourinary system kunye nosulelo lwentsholongwane, le antibiotic inceda kwezi zifo ezilandelayo ezibangelwa yi-enterococcus, i-proteus, i-E. coli okanye usulelo oluxubekileyo:
- i-pielit;
- pyelonephritis;
- urethritis;
- i-cystitis;
- gonorrhea;
- cervicitis.
3. Izifo ze-bile-excreting (biliary) inkqubo ye-Ampicillin iboniswe ukuba:
- cholecystitis;
- cholangitis.
4. I-Ampicillin iyalelwe kubafazi abakhulelweyo xa kukho isifo se-chlamydial, ukuba kukho ukunganyamezelani ku-Erythromycin.
5. Izifo ezithathelwanayo zezicubu ezincinci kunye nolusu, njenge:
- impetigo;
- ubuso;
- udermatosis isigaba sesibini sosulelo;
- amanxeba.
6. Kwiintsholongwane ze-musculoskelet system, ezibonakaliswa kwezi zifo:
- rheumatism;
- arthritis;
- osteomyelitis ;
- listeriosis;
- pasteurellosis.
7. Xa isondlo sesisu sichaphazelwa zizifo ezifana:
- salmonellosis;
- salmonella;
- isifo somhlaza;
- umkhuhlane we typhoid;
- paratyphus;
- peritonitis.
Kwakhona, i-Ampicillin imiselwe izifo ezinzulu kunye neziyingozi njenge-meningitis, endocarditis, sepsis (septicemia okanye ukusuleleka kwegazi), izifo ezithintekayo kwi-oral cavity.
I-Ampicillin ekhatyweni kwe-strep throat
U-Angina isifo esibangelisayo esibangelwa liqela le-streptococcal leebhaktheriya. Indlela efanelekileyo kakhulu yokonyango lwe-streptococcal angina yonyango ngamayeza okulwa neentenicillin, ngokukodwa, i-Ampicillin iintsuku eziyi-10-14.
Kule meko, ukuphuhliswa kosuleleko kuvalwe okokuqala, kuba ukwahlukana nokukhula kwebhaktheriya kuvaliwe, kwaye ngoko isifo sifela ngokukhawuleza ngenxa yokutshatyalaliswa ngonaphakade kweendonga zeseli, ukungakwazi ukubuyisela kunye nokufa kokugqibela kweebhaktheriya ze-pathogenic. Ukuziqhelanisa kubonisa ukuba uncedo luyeza ngosuku lwesibini lokuthatha iyeza, kwaye emva kweentsuku ezine-5 ukuya kwezi-5 iimpawu ziyahamba. Xa unyango lwe-streptococcal angina, umthamo we-Ampicillin kubantu abadala uvela kwi-0.25 ukuya kwi-0.5 grams. Thatha izilwanyana ezine ngosuku.
Unyango lwe-pneumonia nge-ampicillin
I-pneumonia yaziwa ngokuba isifo esithathelwanayo esibangelwa yi-bacterium ye-pathogenic. Kubalulekile ukunyanga i-pneumonia ngokucacileyo, kodwa iindlela eziphambili "zokunqoba" kwesi sifo ziyi-antibiotics. U-Ampicillin uhlangabezana nalo msebenzi ngokufanelekileyo, kungenxa yoko oogqirha baninzi bayayichaza. Kulungile, ukuba usebenzisa i-Ampicillin-sulbactam, ekubeni ine-spectrum eyongezelelekileyo yesenzo kwaye ibhubhisa imiqobo yale mabhaktheriya enqabile kwi-Ampicillin evamile. Njengomthetho, nge-pneumonia, i-antibiotics imiselwe ngokukhawuleza ukuba ungene ngokukhawuleza kwigazi.