I Pradax liyeza elisetyenziselwa ixesha lokuhamba emva kokuthintela i-thromboembolism ye-venous. Ukuba isigulane sinokuchasene nokusetyenziswa kwale mayeza, kuya kuba nzima ukuyibeka endaweni, kuba iPradaxes inamanani ambalwa kakhulu.
Analog Pradax Xarelto
I-Xarelto yi-anticoagulant kunye neyodwa yamanqaku afanelekileyo ase Pradax. Iveliswa ngendlela yamacwecwe. Into esebenzayo yale nkunkuma yi-rivaroxaban micronized. Ngokwenene, eli liyeza lisetyenziswe njengesixhobo sokukhusela ngokubethelwa kwabantu abahluphekayo kwi- fibrillation ye-atrial . Kwakhona, ngenxa yento yokuba i-Xarelto iyasebenza kwaye ibekezeleleka, isetyenziselwa ukuthintela:
- i-thromboembolism enobuhlungu (emva kokugqitywa kwemisebenzi yamathambo amakhulu kumagatsha aphantsi);
- thromboembolism.
Awukwazi ukusebenzisa le mfuziselo yeyeza kaPradax kunye nokuphuma kwamanzi, okuchaphazela iziganeko ezibalulekileyo (umzekelo, isicatshulwa esiswini okanye indawo engenakunyango) kunye nezifo zesibindi ezihamba kunye ne-coagulopathy. Kwakhona, ungayisebenzisi kwezo zi gulane ezingenakukwazi ukuzala okanye ukunyanzelana ukuba zenze i-lactase okanye i-high-sensiti ukuba i-rivaroxaban.
Emva kokuthatha i-Xarelto, iziphumo ezibi zingenzeka. Ininzi idla ngokubonakalayo kwizinga elimodareyithwayo, kodwa liyabangela ukuba izigulane zingabonakali. Ezi ziquka:
- ukukhulelwa kwegazi;
- isicefe
- umsebenzi owandisiweyo weGH;
- ukuphuma kumanxeba.
Kwiimeko ezinqabileyo, isigulane sinomkhuhlane kunye neempendulo.
Analog Pradaxes Warfarin
Ukuba unomdla kwi-analogues ye-Pradax ukulungiselela kuphela kwiiphilisi, enye enye into enobungakanani obuya kutshintshwa yi-Warfarin. Le yinto ecacileyo yezenzo ezingekho ngqo. Faka isicelo sokunyanga kunye nokuthintela u-embolism ye-pulmonary, i-thrombosis ye-venous yeyiphi na ifom kwaye unyule abo bane-fibrillation ye-agriyo. Njengamanye ama-Pradax analogs, iipilisa ze-Warfarin zisetyenziselwa emva kokuphazamiseka ukukhusela iingxaki ze-thromboembolic.
Ukungqinelana kokuthatha eli mayeza ngu:
- isifo se-DVS-syndrome;
- izilonda zeenkqubo ze-renal kunye ne-hepatic;
- ukuphuma kwegazi;
- thrombocytopenia;
- imilenze ye-varicose ye-esophagus;
- i-hemorrhage.
Zonke iimpawu kunye neempawu ezifanayo zePradax zinemiphumo emibi. Kodwa ukuba emva kokuthatha ezinye iipilisi azibalulekanga, ngoko iWarfarin ingabangela ingozi enkulu emzimbeni. Ngoko, ukusetyenziswa kwayo kunokuvusa ukuvela kwesifo se-dyspeptic, i-coumarin necrosis okanye i-palmar-plantar necrosis.
I-Analogue Pradaxes Angioks
Ukuba unomdla kwi-analogues ye-Pradax enenjongo yokulawulwa kwe-intravenous, i-Angioks yeziyobisi isisombululo esihle. Bafanisa ikhowudi ye-ATC yezinga le-4. Ii-angiok zi-anticoagulant ngqo. Iveliswa njenge powder lyophilized, esetyenziselwa ukulungiselela isisombululo.
Into esebenzayo yale nkunkuma yi-bivalirudin trifluoroacetate. Ngokuqhelekileyo basebenzisa ii-Angiok njenge-anticoagulant ekulawulweni kwe-PTCA (ukungenelela kwe-coronary intercutinal). Ikwasetyenziswa kwakhona kwi-infyoction ye-myocardial okanye i-angina engaqinisekanga. Kunconywa ukuyikhetha ngexesha elifanayo kunye ne-clopidogrel kunye ne-acetylsalicylic acid.
Ama-angiok kufuneka athathwe ngokulandelelanayo emva kwesilinganiselo, kuba, njengamanye amafanane ka Pradax, eli phephelo lingenza iziphumo ezibi
- ukuphuma kwamanzi kwiindawo ezahlukeneyo;
- ukukhulelwa kwegazi ;
- ukukhawuleza;
- isicaphulelo.
Ukungqinelana kwonyango olunjalo ngonyango:
- ukuphuma kwegazi;
- ukuxhathisa i-bacocial endocarditis;
- i-hypersensitive to bivalirudin;
- ukungaphumeleli komzimba.