I-AMG-hormone (i-antimulylerovskiy hormone) okanye, njengokuba ibizwa nangokuthi-into e-inhibitory ye-Muller, inoxanduva lokwahlukana kobulili bombindi, kubandakanyeka ekutshatweni kobugqwetha kunye ne-spermatogenesis. Esi sibonakaliso sisoloko sisetyenziselwa ukuchonga izizathu zokungabikho kwindoda kunye nokungabikho kwamadoda , kunye nokuxilongwa kwezidumbu ezithile.
I-AMG yinto evamile kubafazi
Ukususela ekuzalweni ukuya ekuqhelweni komntu kwabasetyhini, le hormone iveliswa ngama-granular cells e-ovarie, kwaye amanqanaba aphezulu afunyanwe kwiiseli zesisu. I-AMG yabasetyhini ichazwa ukuze ichonge ukukhawuleza okanye ukusa komntwana, ukuseka isondo, xa lo mbuzo ubizwa ngokuba ngumbuzo, ekuxilongweni kwegranulosa cell carcinoma yama-ovari kunye nakwezinye iimeko.
Ukongezelela, i-antimulylerov hormone icetyiswa ukuba ithathe ukulungiselela i-IVF. Olu hlalutyo lwenziwe kwiintsuku ezithile zomjikelezo, ngelixa umlinganiselo we-inhibitor B ukuya kumgangatho we-AMN uvavanywa. I-IVF, izinga le-AMG-hormone kufuneka libe yi-0.8 ng / ml.
Ngokuqhelekileyo, ngexesha lokuzala, ukuxinwa kwe-AMG kwabasetyhini ngokuqhelekileyo kuhlala ngo-2.1-7.3 ng / ml. Ukuba izinga le-hormone linciphisa ukuya kwi-1.1 ng / ml kwaye lusezantsi, ngumbuzo wokunciphisa indawo yokusebenza yamaqanda. Kwaye kuncipha ngokukhawuleza kule ndawo, ixabiso liyancitshiswa libe yi-0.8 ng / ml kwaye liphantsi.
I-AMG ne-IVF ephantsi
Ukuncipha okunjalo kumgangatho osisiseko we-AMG ubonisa ukuba amathuba okukhulelwa ngexesha le-IVF. Izigulane ezineendawo ezincitshisiwe zokugcina ii-ovari kunye ne-anti-Muller level hormone zenza okubi ngakumbi ekukhuthazeni ezenziwa kwinqanaba lokuqala lohlelo lwe-in vitro fertilization.
Ukongezelela, izinga le-AMG kwi-IVF lihlolwe ukwenzela ukuvavanya umngcipheko wokuvuselela okunjalo. Ngamanye amaxesha le nkqubo ikhokelela kwisimo esisongela ubomi-isifo se-ovarian hyperstimulation. Njengoko lwazi, unokwenza ucwangciso lwenkqubo yokwelashwa kwabantwana.
Ungalungiselela njani uhlalutyo?
Ukuqhuba ukuhanjiswa kwe-AMG kufuneka ulandele ezinye iingcebiso:
- ungadli iiyure ezingama-12 ngaphambi kokuba inkqubo;
- Kubalulekile ukuba ungabandakanyi ngokupheleleyo ukungenisa i-androgens kwisithuba seeyure ezingama-48 ngaphambi kokunikezelwa kwegazi;
- Musa ukutshaya ubuncinane isiqingatha seyure ngaphambi kokuhlalutya;
- Kunconywa ukuba kuqhutywe uhlalutyo ngosuku lwesithathu okanye lwesi-4 lomjikelezo wesini.
Ukuhlalutya, lona wesifazane uthatha igazi elinomdla, kwaye indlela yokuphanda kwimeko enjalo i-enzyme immunoassay. Iiyunithi zokulinganisa zi-nanogram nge-milliliter (ukuxinwa kwezinto ezikhoyo kwigazi lilinganiswa).