I-OH-progesterone okanye i-pro-protheone ye-17-OH ayikho ihomoni, nangona okokuqala ingcinga yegama yiloo nto. Enye yamagama ayo anama-17-OH, i-17-OPG, i-17-alpha-hydroxyprogesterone. Kodwa kungakhathaliseki ukuba kubizwa njani, ifunyenwe ngenxa ye-metabolism ye-hormone ye-steroid efihliwe ngama-ovari kunye ne-correx ye-adrenal.
I-progesterone ye-17-OH iyimveliso ebalulekileyo ekugqityiweyo, apho i-hormone yenziwe khona. Inqanaba elinciphile okanye eliphakanyisiweyo le nkunkuma akufanele kubangele ukukhathazeka ngexesha lokukhulelwa. Nangona kunjalo, kwamanye amaxesha, oku kufuneka kuphawule.
Ukuba i-progesterone ye-17-OH iyancitshiswa
Ukuba izinga le-17-OH progesterone liphantsi ngexesha lokukhulelwa, alinasisongela umntwana. Ngeli thuba, ukuhlolwa kwegazi akuboneleli ngolwazi oluncedo kumgqirha kunye nesigulane. Kubaluleke ngakumbi ukufumanisa umgangatho weprogesterone kumntwana emva kokuzalwa.
Ngokubanzi, uhlalutyo lwe-progesterone ka-17-OH luthathwa ngosuku lwesine-5 lwenyanga yokuya esikhathini. Yenza oku kungekho ngaphaya kweeyure eziyi-8 emva kwesidlo sokugqibela. Kukho imimiselo ethile yokuxinwa kwale nkunkuma, kuxhomekeke kwisigaba somjikelezo kunye nobudala bomfazi. Xa ukhulelwe, kukho ukunyuka kwi-17-OH progesterone.
Ukuba i-progesterone ye-17-OH iyancipha (asikhulumi ngethuba lokukhulelwa), oku kubonisa ubuninzi beemvakalelo emzimbeni, njengale:
- Isifo sika-Addison (ukungapheli okungapheliyo kwe-correnx ye-adrenal);
- Ukungalunganga kwezitho zozalana kumakhwenkwe.
Ukuba ibhinqa linobungozi bentsholongwane ye-correnx ye-adrenal, oku kunokukhokelela ekungabikho komntwana , nangona iimeko ezibonakalayo zingabonakaliswa kwaye loo nto ibhinqa ngokukhawuleza kwaye iyazala.
Nangona kunjalo, ukuba unokwenza okungaqhelekanga kwimveliso ye-17-OH progesterone, qhagamshelana neengcali. Kukho onke amathuba onokukwenza, ngoncedo lwenyango efanelekileyo ngexesha elifanelekileyo, ukulungelelanisa izinga lezinto kwaye ukhuphe imiphumo emibi.