Uhlalutyo lokumisela izinga le-AMG (i-antimulylerov hormone) lucetywayo malunga nangoko-ngo-2002. Emva koko abaphandi baqaphela ukuba abafazi bavuselela ngaphambi kwe-IVF kunye nenani le-oocytes elithotyelwe ngaphantsi kwama-6 lahluke kwii-oocytes ezili-11 okanye ngaphezulu ngokwezinga le-AMH, elilinganiselwe ngaphambi kokuvuselela. Iyokuqala yayisukela kwi-1 ukuya ku-0.4 ng / ml, kanti ekupheleni, eli nqanaba lalingama-2.5 ukuya ku-0.3 ng / ml.
Emva koluhlu lwezifundo, izazinzulu ziye zafikelela kwisigqibo sokuba i-AMG ingasetyenziselwa ukuba ibe ngumqondiso we-ovarian reserve. Indawo yokugcina i-ovari yindawo yokusebenza yama-ovari, ebonisa ukuba amandla okomama ukuphucula i-follicles enempilo kunye ne-ovum epheleleyo, kunye nokuphendula okwaneleyo ngexesha lokukhuthaza.
Ukuba i-antimulylerov i-hormone engezantsi isisindo okanye isilinganiselo
Iqondo le- hormone ye- antimulylerovoy kubasetyhini abaqhelekileyo kuxhomekeke, okokuqala, xa bebudala. Xa uneminyaka eyi-9, le hormone idla ngo-3.5 ng / ml. Kwimihla yokuzala, oko kukuthi, kwiminyaka eyi-15 ukuya kwe-41, ngokuqhelekileyo izinga le-AMG lisuka kwi-2.1 ukuya ku-7.3 ng / ml. Ngokuqala kokuphuma kwesisu, izinga le-hormone linciphisa ukuya ku-0-1 ng / ml.
Ngelishwa, ngaphezu kwexesha lokumisa umva, i-anomie kunye ne-dysgenesis yama-ovari, i-chemotherapy, indawo ephantsi yokusebenza yama-ovari kunye ne-syndrome ye-mullerian conduit eqhubekayo inokuchaphazela ukunciphisa kwinqanaba le-hormone ye-antimulylerovogo.
Xa i-antimulylerov i-hormone kumfazi iyancitshiswa, ingaba sisizathu seengxaki zokukhulelwa komntwana ngokwemvelo. Kwaye kuncipha ngokukhawuleza kwiindawo zokugcina ii-ovaries, kuba nzima ukukhulelwa nangona uncedo lwe-IVF, kuba kukho impendulo enganeleyo ekukhuthazeni.
I-antimulylerov hormone ephantsi kunye nokukhulelwa
Ekubeni i-ovaries yokugcina i-ovari iyancipha kunye nobudala, akukho ncamango ekukhuselweni kokuhlehliswa "ukukhupha". Kuboniswa ukuba ukuba ibhinqa lineminyaka engama-31 ubudala, amathuba okuzimela
Iminyaka engamashumi amane nanye idla ngokungafumaneki. Uhlalutyo lwe-AMG lunceda ekucaciseni ixesha eliqikelelweyo lokungabikho kwengqondo. Akuyi kuba yinto engathandekiyo ukuthabatha le nkcazo kubafazi abancinci ngexesha lokucwangcisa ukukhulelwa .
Ukuba kukho i-hormone ye-antimulylerov ephantsi (AMG), ibonisa ukuqala kokumisa kwimizuzu kwiminyaka emihlanu ezayo. Ubunokwenzeka bokuzikhusela ngokwamanqanaba aphantsi kwe-AMG (i-antimullerovym hormone) iyancitshiswa, nangona kukho iimeko xa abafazi kunye neqondo eliphantsi kakhulu le hormone banakho ukukhulelwa umntwana.