Androgens kwabasetyhini - iimpawu

I-Androgens-iqela le-hormone yesini, iveliswe zombini nakwimzimbeni yabesifazane. Kodwa zithathwa njengomntu, kuba phantsi kweempembelelo zawo kukho ukubunjwa kwezinto zesini zesibini ngokuphathelele kwindoda yesilisa. Kwimizimba yabasetyhini, i-80% ye-androgens yimeko ehambelanayo, engasebenzi. Kodwa esinye sezifo eziqhelekileyo zesimo se-endocrine - i- hyperandrogenism - yindoda engaphezulu kwama-androgens kwabasetyhini. Kubangele ukuphazamiseka ezininzi kwiimeko zempilo kwaye kubangelwa izizathu ezahlukeneyo.

Ngokuqhelekileyo, uhlalutyo lwe-androgens kwabasetyhini alubonakali ukwanda kwinqanaba labo egazini, kwaye eso sifo sibangelwa kulokhu ngokuphula umthetho obophekileyo be-hormone kunye neprotheyini ekhethekileyo kunye nokungakwazi ukubola kwe-androgen kunye nokukhutshwa kwabo emzimbeni. Oku kudla ngokuba ngenxa yezifo zofuzo kunye nokuveliswa kwemiphumo ye-enzymes ethile.

Iimpawu ze-androgens ezingaphezu kwezilwanyana

Iimpawu ze-hyperandrogenism kwabasetyhini:

• u-hirsutism, okanye ukukhula kweenwele kwintlobo yesilisa - ukuvuselela i-androgenic izinwele zeentloko zikhokelela ekukhuleni kweenwele ezinzima zobuso ebusweni, kwisisu okanye esifubeni;
• i-acne, i-seborrhea kunye nezinye iingxaki zesikhumba zibangelwa ngumsebenzi ogqithiseleyo weengqungquthela ezixhambileyo phantsi kweempembelelo ze-hormone zesini;
• Ukulahleka kweenwele kunye ne-alopecia ziyimfuneko ebunzini;
• kuncipha ngezwi lezwi;
• iziphene zonyango ezibangelwa lizinga lokunyuka kwama-androgens kwabasetyhini zivame ukudala ukuphazamiseka kwengqondo, ukuzimela kunye nokudandatheka;
• izifo zentsholongwane, ngokomzekelo, i-polycystic ovaries, i-amenorrhea, ukungabikho kwemvelo kunye ne- endometrial hyperplasia ;
• Ukuphulwa kwemali ye-hormonal kubangela iingxaki ze-endocrine kwaye kunokukhokelela ekubonakaleni kwesifo sikashukela, ukukhuluphala kunye ne-lipid metabolism.

Unyango lwe hyperandrogenism

Ukukwazi ukunciphisa i-androgens kwintombazana, ugqirha kufuneka ahlolisise ngokupheleleyo kwaye achaze isizathu salo mqathango. Emva koko, kunokubangelwa ukuphulwa kwemisebenzi yesibindi, ukusilela kwe-vitamin okanye ukulawulwa kweziyobisi ezithile, umzekelo, iGestrinone, iDanazol okanye i-corticosteroids. Ukuba isizathu sokuba i-androgens kwindoda ibhinqa ngamanye, ke ukusebenzisa izidakamizwa ze-antiandrogenic, umzekelo, uDiane-35, uZhanin okanye i-Yarin, inokwenzeka. Ugqirha unokuthatha kwakhona ezinye iziyobisi ezikwazi ukulungelelanisa ibhalansi ye-hormonal.

Kodwa kwiminyaka yakutshanje, izazinzulu ziye zafumanisa ukuba kuyingozi nje kuphela ukunyuka, kodwa kwanokungabikho kwe-androgens kwabasetyhini. Le meko ingabangela izifo zentliziyo, ukuphuhliswa kwe-osteoporosis kunye nokuncipha kwinqanaba le-hemoglobin. Ngoko ke, kulunge xa ​​ama-hormone egazini aqhelekileyo.